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Drinking Water and Health, Volume 5 (1983) / Chapter Skim
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Carbon tetrachloride
Pages 15-18

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From page 15...
... CARBON TETRACHLORIDE methane, tetrachIorm CAS No. 5~23-5 CCl4 Carbon tetrachloride was evaluated in the first and third volumes of Drinking Water and Health (National Research Council, 1977, pp.
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From page 16...
... may also forte under anaerobic conditions in hepatic microsomes (Ahr et al., 1980~. Inhibitors of cytochrome P450 decrease carbon tetrachloride toxicity, whereas Type I inducers of cytochrome P450 enhance the hepatotoxicity (National Research Council, 19801.
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From page 17...
... In summary, carbon tetrachloride was mutagenic in one microbial mutagenicity assay. Carcinogenicity The carcinogenicity of this compound was evaluated in the first volume of Drinking Water and Health (National Research Council, 1977, pp.
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From page 18...
... CHLOROBENZENE monochlorobenzene; benzene' chlorine CAS No. 108-90 7 Cl Chlorobenzene was reviewed in the first volume of Drinking Water and Health (National Research Council, 1977, pp.
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Key Terms

  • lipid peroxidation
  • drinking water
  • trichloromethyl radical
  • reduced survival
  • saccharomyces cerevisiae

  • survival rate
  • induce lipid
  • tetrachloride toxicity
  • inhalation exposures
  • mitotic recombination

  • offspring exposed
  • membrane function
  • inducing lpo
  • aspartate aminotransferase
  • enhanced toxicity

  • exquisite sensitivity
  • carbon monoxide
  • administered orally
  • female rats
  • tetrachloride proceeds

  • toxic inhalation
  • gene conversions
  • acute effects
  • diaz gomez
  • rats exposed

  • reduce fetal
  • triglyceride accumulation
  • effects carbon
  • fetal size
  • reactive trichloromethyl


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