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Pages 248-248

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From page 248...
... In order to trace the evolutionary origins of aggressive behavior at the behavioral, physiologic, and neurobiologic levels, detailed functional and structural analyses at each level are needed; this need is particularly acute at the behavioral and diagnostic levels. NEUROCHEMISTRY AND NEUROPHARMACOLOGY OF AGGRESSION AND VIOLENCE Until the development during the last decade of microdissection and imaging techniques for neural tissue, as well as techniques for in viva microdialysis and improved sensitivity of biochemical assay, the evidence for the involvement of ACh, gamma-aminobutyric acid {GABAJ, NE, DA, and 5-HT in neural mechanisms of animal aggression was based entirely on single measures that summarized an experimental subject's entire brain activity at one time point.


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