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Improved Fire- and Smoke-Resistant Materials for Commercial Aircraft Interiors A Proceedings (1995) / Chapter Skim
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Session I: Toxicity
Pages 224-227

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From page 224...
... Army Marcelo Hirschler, Safety Engineering Labs Thomas Murray, Boeing Commercial Airplane Group David Purser, Fire Research Station Henry Roux, Rowr International Chuck Williamson, General Plastics Manufacturing Co. SESSION REPORT The following views and suggestions were presented by one or more participants in this session.
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From page 225...
... · Include analytical characterization and model prediction, followed by a limited bioassay proof test using animals that best represent human responses. Incorporate heat, hot-water vapor, and particulates into predictive toxicity potency models (e.g., N-gas and FED [fractional effective dosed.
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From page 226...
... The major fire scenarios of importance in aircraft are (~) a post-crash pool fire resulting from ignition of aircraft fuel penetrating into the cabin following aircraft skin rupture; (2)
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From page 227...
... Research should include the following: investigation of effects on humans, both survivors and fatalities, from actual aircraft Walrus; development of a smoke toxicity test with proven validity for aircraft scenarios; potential investigation of effects due to hot-water vapor, particulates, and free radicals; potential investigation of in vitro methods for toxicity targets; and investigation of potential chronic effects of acute exposures to fire.
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Key Terms

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  • fire hazard
  • limiting factor
  • toxic effects
  • decomposition products

  • potential investigation
  • fire environment
  • smoke obscuration
  • free radicals
  • workshop session

  • toxic decomposition
  • relevant toxic
  • bioassay proof
  • surrounding fire
  • labs thomas

  • predictive toxicity
  • vitro methods
  • aircraft skin
  • primary cntenon
  • issues surrounding

  • toxicological effects
  • test using
  • short distance
  • fire resulting
  • chronic effects

  • human lethality
  • requirements relevant
  • toxicity considerations
  • potential chronic
  • methods exist


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