Skip to main content

Chemical Ecology The Chemistry of Biotic Interaction (1995) / Chapter Skim
Currently Skimming:

Index
Pages 205-214

The Chapter Skim interface presents what we've algorithmically identified as the most significant single chunk of text within every page in the chapter.
Select key terms on the right to highlight them within pages of the chapter.


From page 205...
... By using high throughput assays, pharmaceutical companies can rapidly scan the contents of tens of thousands of extracts of microorganisms, plants, and insects. A screen may be designed to search for compounds that affect the activity of an individual targeted human receptor, enzyme, or ion channel, or the screen might be designed to capture compounds that affect any step in a targeted metabolic or biochemical signaling pathway.
Read the entire page →
From page 206...
... However, if a drug discovery target contains regions of structure homologous to that in other proteins, structures known to interact with those proteins may prove useful as leads for a medicinal chemistry effort. The specificity of a lead for a target may be optimized by directing structural variation to specificity-determining sites and away from those sites required for interaction with conserved features of the targeted protein structure.
Read the entire page →
From page 207...
... Chemical Ecology: A View from the Pharmaceutical Industry /199 Currens, M l., Buckheit, R
Read the entire page →
From page 208...
... (1992) Secondary Metabolites: Their Function and Evolution, Ciba
Read the entire page →
From page 209...
... (1989) in Primary and Secondary Metabolism of Plant Cell Cultures, ed.
Read the entire page →
From page 210...
... Drug Discovery Des.
Read the entire page →
From page 211...
... Abbreviations 9-HPEPE 9-hydroperoxyicosa-(5Z, 7E, llZ, 14Z, 17Z) -pentaenoic acid AL antenna!
Read the entire page →
From page 212...
... 204/ Abbreviations MHC major histocompatibility complex NF-AT nuclear factor for activated T cells olfactory receptor cell PA pyrrolizidine alkaloid PB diet pinto bean-based diet Ph-I==0 iodosylbenzene PN projection neuron PPIase peptidylprolyl isomerase TCR T-cell receptor TPPMn tetraphenylporphyrinatomanganese
Read the entire page →
From page 213...
... See Poisons, in amphibians Amplitude modulation, 154 Analipus japonicus, 92 Ant communication system, 41 modulatory communication, 45-47, 49 multicomponent signaling, 43, 4647, 48-49 nestmate recognition, 47-48 signal ritualization, 44-45 signal specificity, 44 social organization, 41 stridulatory vibration, 45-46 trail pheromones, 42-44 Apiomerus flaviventris, 129
Read the entire page →
From page 214...
... 206 / Index Arthropods chemical defenses, 30-34 chemical eavesdropping strategies in predation, 52-54, 63 chemical predatory strategies, 62-63 chemical signaling in predation, 51-52 predatory mimicry by spiders, 59, 63 as source of frog/toad toxins, 24-26 spider venoms, 34-36 See also Lobster Atelopus toads, 18 Azabicyclononane, 33 Azamacro lid es, 33, 3 8 Azaphenalene, 33 B Batrachotoxins actions of, 23 in amphibians, 22-23, 26, 191 in birds, 23 Beet armyworm, 55-57 Benzoyl cyanide, 30 Bioinformatics, 192 Birds, 122 chemical defenses in, 4 poisonous substance production, 17 Bolas spider, 59-61 Bombesin, amphibian skin, 18 Bombyx mori, 105 Brachycephalus toads, 18 Bradykinin, amphibian skin, 18 Bufadienolides, 18, 22, 31 Bufo toads, 18 6-(lE) -Butenyl, 92 Butylbenzene, 99 C Caerulein, amphibian skin, 18 Calcineurin, 137, 138, 139-140, 143, 187 Camouflage, in chemical signaling, 148 cAMP, 110 Campoletis sonorensis evolution, 78-80 expression patterns, 80 induced developmental arrest of host larva, 68-69 polydnavirus expression in host, 70-78 polydnavirus gene families, 79-80 polydnavirus protection for, as endoparasite, 67-68, 81 polydnavirus structure, 69-70, 82 protection from host recognition, 67-68, 81-82 Cannibalism, 128-129 Cantharidin, 129 Caprylic acid, 30 Carbon metabolism biosynthesis of Cal hydrocarbons in plants, 92-98 in plant defense, 8-9 Cassava, 58 Caudoxirene, 91 Cell death, 187 Ceratopogonid flies, 54 Chemical signaling agricultural application, 62 algal pheromones, 87-92 in ant social organization, 41 ant trail pheromones, 42-44 arthropod predation, 51-52, 62-63 camouflage, 147, 148 dispersal patterns, 148 evolutionary development of olfaction, 162-164 immunophilin / immunosuppression complexes, 136-140 lobster urine, 154-158 in marine environment, 148-150 modulatory communication in ants, 45-47, 49 molecular interaction, 142-143 multicomponent systems in ants, 43, 46-47, 48-49 multidisciplinary research, 142, 143 nestmate recognition in ants, 47-48 plant, to summon herbivore predator, 54-58, 63 predatory mimicry, 59-61
Read the entire page →

Key Terms

  • chemical signal
  • nestmate recognition
  • modulatory communication
  • trail pheromones
  • secondary metabolites

  • drug discovery
  • social organization
  • signal ritualization
  • protein structure
  • amplitude modulation

  • signal specificity
  • secondary metabolism
  • ant communication
  • amphibians amplitude
  • multicomponent signaling


    • This material may be derived from roughly machine-read images, and so is provided only to facilitate research.
    More information on Chapter Skim is available.