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Vaccines for the 21st Century A Tool for Decisionmaking (2000) / Chapter Skim
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Appendix 22: Rotavirus
Pages 291-294

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From page 291...
... Disease Scenarios For the purposes of the calculation in this report, the committee assumed that rotavirus infection is associated with 8 days of acute diarrhea and a health utility index of.75. COST INCURRED BY DISEASE Table A22-1 summarizes the health care costs incurred by rotavirus infections.
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From page 292...
... During the time the committee report was in final stages of analysis and preparation, the rotavirus vaccine was approved for licensure. Table 4-1 summarizes vaccine development assumptions for all vaccines considered in this report.
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From page 293...
... If a vaccine program for rotavirus were implemented today and the vaccine was 100% efficacious and utilized by 100% of the target population, the annualized present value of the health care costs saved would be $225 million. Using committee assumptions of less-than-ideal efficacy and utilization and including time and monetary costs until a vaccine program is implemented, the annualized present value of the health care costs saved would be $120 million.
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From page 294...
... Smith JC, Haddix AC, Teutsch SM, et al. Cost-effectiveness Analysis of a Rotavirus Immunization Program for the United States.
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Key Terms

  • target population
  • rotavirus infection
  • committee assumptions
  • using committee
  • rotavirus vaccine

  • including time
  • care costs
  • monetary costs
  • costs saved
  • vaccine development

  • committee assumed
  • qaly gained
  • program cost
  • summarizes vaccine
  • disease burden

  • vaccines considered
  • rotavirus immunization
  • vaccine strategy
  • program considerations
  • qaly saved

  • calculated cost
  • decreases slightly
  • infection incur
  • immunization program
  • final stages

  • rotavirus vaccines
  • annual birth
  • disease reduction
  • currently licensed
  • infection leads


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