Biographical Memoirs Volume 51 (1980) / Chapter Skim
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Robert Kho-Seng Lim
Robert Kho-Seng Lim
Pages 280-307
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From page 280... ...
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From page 281... ...
In the first, he was a physiologist with research interests in the control of gastric secretion and the neurophysiology of pain. He establishecl Western physiology in China while teaching at the Peking Union Medical College.
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Lin. Robert Lim's father, Lim Boon Keng, dic3 so well as a poor boy at the Raffles Institution in Singapore that he won the Queen's Scholarship to Edinburgh University where he graduated in medicine.
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The next year Lim presented the results of his research to earn the Ph.D. In the tradition of British physiology, microscopic anatomy came within the purview of the Physiology Department, and Lim cleveloped skill in histological techniques and observations.
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Ec~kins had shown, by methods very similar to those of Bayliss ant! Starling, that extracts of the gastric antral mucosa stimulate secretion of acid by the oxyntic mucosa, and he had postulatec!
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The Peking Union Medical College had been developed by the China Medical Board with an endowment from the Rockefeller Foundation. In 1915 the Board, with the advice of W
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E Ferguson, China Medical Board and Peking Union Medical College (New York: China Medical Board of New York, Inc., 1970)
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. our work proves that E6kins' pyloric hormone theory is utterly inadequate; that there is either no hormone mechanism, or, if one, that the whole gastro-intestinal tract is involved."*
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Lim occupied a fully equipped Physiology Department, and during his tenure from 1924 to 1938 he hacl a staff of seven professionals, five of them Oriental. The China Medical Board sent visiting professors to P.U.M.C., and the list is an honor roll of American meclical science.
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From page 289... ...
The efferent pathway goes unilaterally clown the ventrolateral columns of the spinal cord, and through it both sympathetic neurones and the adrenal medulla are excited. Stimulation of the central end of the cut sciatic nerve has its familiar presser effects mediated by the center Lim described.
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Lim used this method to study humoral transmission in the central nervous system. In this case, the organ perfused was the severed head of a donor dog.
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a training corps for reserve medical officers. As the Japanese attacks began, Lim founded the Chinese Red Cross Medical Relief Commission, and its field units first saw service when the Japanese mover!
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On Taiwan, Lim built the National Defense Medical College and ten hospitals throughout the islancI. Lim regretted that he had lost touch with teaching and research, and after twelve years of fighting uncier desperate circumstances, he wanted to return to the academic life.
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From page 293... ...
in some instances Lim placed electrodes on the nerves so that afferent impulses coulct be recorded. Intra-arterial injection of a minute amount of braclykinin into the spleen tract no effect upon the (donor dog, but the recipient dog gave a brief affective response, that is, it howlecl, struggled, and bit.
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The nomination lists as his qualifications his scientific accomplishments, his stimulation of physiological research in China and his promotion of Western medicine there. It also cites his services to China, then our ally, in organizing the Medical Relief Corps, in providing medical and surgical services for the Chinese armies ant!
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ROBERT KHO-SENG LIM 295 IN ADDITION to the staff of the Rockefeller Archives Center already identified, I thank Ms. Opal Gunter of Miles Laboratories, Inc., M
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(Hon. Causal, 1961, Hong Kong PROFESSIONAL RECORD 1919-1923 Lecturer in Physiology, Edinburgh University 1920 Goodsir Fellow, Edinburgh University 1923- 1924 Rockefeller Foundation Fellow, University of Chicago 192~1938 Professor and Head, Department of Physiology, Peking Union Medical College 1939-1941 Director, Emergency Medical Service Training School 194~1947 Special Lecturer in Physiology, Columbia University 1945 Organizing Director, Institute of Medicine, Academia Sinica 194~1949 Director, National Defense Medical Center, Republic of China 1949~1950 Visiting Research Professor of Clinical Science, Uni versity of Illinois, Chicago 195~1951 Professor and Head, Department of Physiology and Pharmacology, Creighton University 1952-1967 Miles Laboratories, Inc., Elkhart, Indiana, Director, Medical Sciences Research, Senior Research Fellow 196~1969 Visiting Professor of Physiology, University of Cali fornia, Los Angeles, and Senior Medical Investigator, Veterans Administration Center, Los Angeles PROFESSIONAL AND HONORARY SOCIETIES British Physiological Society, 1919 Fellow, Royal Society of Edinburgh, 1923 American Physiological Society, 1923 Sigma Xi, 1924 Society for Experimental Biology and Medicine, 1925 President, Chinese Physiological Society, 1927 President, Chinese Medical Association, 192~1930 Honorary Member, Deutsche Akademie der Naturforscher, Halle, 1932
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RA T I O N S Great Britain: 1914-1915 Star; General Service Medal, Victory Medal, 1918 United States: Legion of Merit, Officer Grade, 1943; Medal of Freedom with Silver Palms, 1946 Republic of China: Kan Ching Medal; Chung Ching Medal; Sheng Li Medal; Yun Hui Order, 1st Class; Victory Medal, 1945
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The "gastrin" content of the human pyloric mucous membrane.
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1924 On the relationship between the gastric acid response and basal secretion of the stomach.
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Hou. Observations on the conduction of the nerve impulse in the cooled phrenic nerve.
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Hou. Factors regulating splenic contraction during exercise.
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Liu. Depressor substances in extracts of the intestinal mucosa.
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III. Central vagus transmission after hypophysectomy in the cat.
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Braun. Visceral pain and pseudoaffective response to intra-arterial injection of bradykinin and other algesic agents.
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Braun. The visceral receptors concerned in visceral pain and the pseudoaffective response to intra-arterial injection of bradykinin and other algesic agents.
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Fulp. Central nervous system activity associated with the pain evoked by bradykinin and its alteration by morphine and aspirin.
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