A Review of the Department of Defense's Program for Breast Cancer Research (1997) / Chapter Skim
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7 Conclusions and Recommendations
7 Conclusions and Recommendations
Pages 97-106
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From page 97... ...
Among the most outstanding features of the program are the flexible approach taken for setting priorities annually; the involvement of breast cancer survivors (consumers) in the grant peer review process; the level of commitment and diligence of the individuals who serve the program in various capacities; the commitment and support of the program director; the low administrative costs that allow the greatest share of funding resources to be awarded as grants; the use of outside experts for evaluation; and the unwavering respect and advocacy for this program among breast cancer advocacy organizations nationwide.
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From page 98... ...
and the deadline for grant applications, and exacted an unduly heavy toll in time and energy on those involved in the various stages of the process. Based on abstracts of projects funded in the 1993/1994 and 1995 cycles, the committee determined that the portfolio covers science that is responsive to the range of six questions posed in the 1993 IOM report.
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From page 99... ...
Elements of the process could include examination of records of publications and presentations, success by investigators in obtaining other grant support relevant to breast cancer, and identification and tracking of investigators who were recruited into breast cancer research by BCRP funding. Program evaluation should also measure achievements of the programmatic aims outlined in the 1993 IOM report.
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From page 100... ...
By functioning as a second-tier (programmatic) review and council, and reporting to contractors and predominantly nonscientific administrators within the Army, the IP wields considerable power in deciding investment strategies and funding policy.
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From page 101... ...
This would facilitate assignments of applications to the most appropriate panels and recruitment of the best and most appropriate ad hoc reviewers. Special emphasis panels may need to be constituted to deal with diverse emerging research directions and multidisciplinary proposals.
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From page 102... ...
This would allow the optimal use of available money toward reaching the goals of the project. RECOMMENDATIONS FOR FUTURE RESEARCH DIRECTIONS The 1993 IOM report identified six questions on the causation, prevention, screening, detection, diagnosis, and optimal treatment of and recovery from breast cancer that were to be used as a framework for breast cancer research.
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From page 103... ...
Furthermore, novel therapies capable of eliminating or terminally differentiating breast cells carrying the genetic changes predisposing to malignancy could be developed. The development of such gene therapy requires a better understanding of the genetic and immunological basis of breast cancer, with the vaccine approach to prevention and treatment facilitated by knowledge of the new altered gene products and peptides expressed in cancer cells..
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From page 104... ...
Furthermore, since 1993, women with breast cancer have had increasing influence in discussions relating to the direction and content of breast cancer research; and they will continue to do so. For example, in testimony to this IOM committee, consumers have asked for additional research in the areas of prevention and treatment of lymphedema, long-term effects of axillary node dissection, living with metastatic disease and treatment for it, hormone replacement therapy for menopause, detection and prevention measures for women with inherited susceptibility to breast cancer, and weight management.
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From page 105... ...
Studies regarding ethnic, cultural, and personal differences in health beliefs and health care seeking behavior will yield important information for those providing care and setting policy. Also necessary is accurate, reliable, unbiased information on direct and indirect costs associated with genetic testing, prevention strategies, screening and diagnostic techniques, or a given treatment; such information is a critical component of realistic health care planning and delivery.
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