Pharmacokinetics and Drug Interactions in the Elderly and Special Issues in Elderly African-American Populations Workshop Summary (1997) / Chapter Skim
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1 INTRODUCTION
1 INTRODUCTION
Pages 1-6
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In addition, the workshop was intended to update a 1990 report by the IOM Forum on Drug Development, Drug Development for the Geriatric Population. In response to this request, the IOM formed a Committee on Pharmacokinetics and Drug Interactions in the Elderly and selected members with expertise in the relevant disciplines including basic science and clinical pharmacology, geriat ~Note: The terms drug and medication are used interchangeably throughout this report.
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Diverse levels of physical health and overall well-being make it difficult to categorize what constitutes "normal aging." Within each of the subgroups of people over 60 years of age, individual biological responses to aging are affected by a range of physiological, genetic, socioeconomic, and environmental factors including nutrition, access to medical care, smoking, and weight. Further, the over-60 subgroups vary widely in physical, emotional, and mental health, social fimction, activity levels, and overall vitality.
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The portion of the population aged 85 and over (the "oldest old") is the most rapidly growing elderly age group, and this group typically has the highest incidence of chronic disabling diseases and He highest health care expenditures.
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in 1991, it is estimated that the elderly population spent between $12.7 billion and $14.3 billion (Long, 1994~. The frequent presence of coexisting illnesses and the use of multiple medications by the elderly increases the potential for drug interactions.
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In addition, the committee extends its appreciation and thanks to Marcellus Grace, Burde Kamath, and many other individuals on the staff of Xavier University of Louisiana who helped plan the IOM workshop and who graciously welcomed the committee, the workshop participants, and the workshop attendees (see Appendix)
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Washington, DC: National Academy Press. Institute of Medicine (IOM)
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