Research Priorities for Airborne Particulate Matter I. Immediate Priorities and a Long-Range Research Portfolio (1998) / Chapter Skim
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5. The Committee's Research Investment Portfolio
5. The Committee's Research Investment Portfolio
Pages 98-105
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From page 98... ...
In developing the research portfolio, the committee sought to integratethe scientificvalue, decisionmaking value, feasibility, sequencing, and rough but informer! collectivejucigment estimates ofthe costs of the recommendeci research activities.
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From page 99... ...
The committee believes that the 1998-2010 time span is an interval over which a comprehensive research program could be reasonably anticipated to produce findings that would materially address key uncertainties in a deliberate plan that emphasizes both early and longer-term results. But the pace of research cannot always be adjusted to match the schedule of a regulatory decisionmaking process, which is determined mainly by law, policy, and administrative factors.
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From page 100... ...
Observational and experimental epidemiological studies are mostly deferred until later in the portfolio plan, pending the development of better methods to measure exposure and an enhanced understanding of the healthrelevant characteristics of particles. In Table 5.l, the committee's research plans for human exposure assessment appear first, front-Ioacled into the early years ofthe portfolio, because there is an urgent need to characterize actual exposures of potentially susceptible persons to particulate matter and to characterize the biological consequences of those exposures.
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From page 102... ...
Monitors will also be needed for use in epidemiological studies directed at particles (or their markers) that are found in the initial years ofthe research portfolio to be linked to toxicity.
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From page 103... ...
The research portfolio also includes epidemiological studies needed to assess the effects of population exposures and to document any biological consequences of changing exposures. In the committee's proposed schedule, funding for major epidemiological studies is deferred until initial planning is accomplished and more information becomes available on exposure measurements for susceptible indiviciuals and the most biologically important aspects of particles.
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From page 104... ...
Better epidemiological methods are needed to increase the efficiency of studies of large populations using routinely collected data on health outcomes and air-pollutant concentrations and for using those data for surveillance of the health consequences of implementing air-pollution standards. The cost estimates for the research portfolio are not based on a formal budgeting process, but drew on the extensive research and research-management experience and collective judgment ofthe members of this NRC committee (see Appenciix A)
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From page 105... ...
Therefore, future judgments will need to be made on the adequacy of new scientific information to address those uncertainties and on the appropriateness of moving from one phase of the committee's recommended research strategy to another. Nevertheless, a coherent and effective particulate-matter research program will require a strongly iterative process that assimilates and uses the results of the multidisciplinary research recommended in this report.
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