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Keynote Address
Pages 7-10

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From page 7...
... First was the idea that both were information sciences biology about various kinds of biologic information, and the information sciences were about the digitized information in the real world. Second was the idea that the 2 disciplines were on a collision course that our ability to execute biology in the future is going to be determined by our capacity to interact with computer science and applied mathematics.
From page 8...
... The human-genome project has brought us an enormous capacity to assess the kind of information that is expressed in different cells, to convert this expressed information into DNA copies, and to analyze in a normal cell or in the tumor cell how the information varies. The second type of biologic information is the information that ensues when we take an intermediate string of messenger RNA and make a final string of it a protein string of 20 letters that leads to a 3-dimensional structure.
From page 9...
... We can use the fragments to map out genetic features and follow particular genetic markers or, for example, disease phenotypes. We can then localize genes, and there are techniques for identifying them and eventually understanding the information pathways that they are a part of and how they have functioned in causing particular diseases.


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