Hazards Technology and Fairness (1986) / Chapter Skim
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Pages 30-33
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From page 30... ...
between a single charged particle and one or more sites in the DNA of a cell. Evidence for this is the initial "linear, no-threshold" relation between the excess incidence of a quantal response seen in an exposed population of cells (animals)
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. 31 radiation particle or increment of another transforming agent, initiate a cancer or a genetic defect.
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radiation used because such radiations are much more effective per unit dose than are low-LET radiations. The bending over of the curve at higher closes is due largely to competing effects such as killing of "induced?
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From page 33... ...
. From these remarks on the origins of cancer, genetic quantal responses, and their radiobiological initiation, it is evident that the "individual" to be considered under these circumstances is neither the organ nor the person, but rather the individual cell (see Table 1~.
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