Hazards Technology and Fairness (1986) / Chapter Skim
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Pages 80-83
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From page 80... ...
These factors include age, illness, nutritional status, drug use, socioeconomic status, behavioral traits, and occupational and ambient exposures to noxious agents. In-depth analyses of genetic and life-history risk factors have been presented elsewhere (Calabrese, 1978, 1985a, 1985b)
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From page 81... ...
Therefore, persons deficient in the enzyme may be at greater risk from foreign agents such as carbon monoxide, lead, nitrate, nitrite, ozone, and radiation, which attack red blood cells. Another metabolic abnormality that increases the body's susceptibility to toxic chemicals is due to genetic variation in an enzyme called pseudocholinesterase.
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From page 82... ...
, a blood component that regulates repair processes in the lung, render the lung more susceptible to respiratory irritants. SAT deficiencies occur in 4 percent to 9 percent of individuals of northern European descent.
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From page 83... ...
In addition to the genetic disorders that have been mentioned, numerous infectious and noninfectious diseases damage organs and reduce their tolerance to foreign agents (Calabrese, 1978~. For example, diseases can reduce the tolerance of the kidney to heavy metals and flouride, the liver to chlorinated hydrocarbons, the lung to respiratory irritants, and the heart to numerous chemicals.
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