Polycyclic Aromatic Hydrocarbons Evaluation of Sources and Effects (1983) / Chapter Skim
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8 SUMMARY
8 SUMMARY
Pages 383-388
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From page 383... ...
· Study the relationship of PAH measurements to the various defined job categories. A studied control group (non-PAH-exposed)
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With appropriately designed cell-model systems that use various cell types, the relationship of in vivo repair of PAH metabolite-DNA adducts should be examined and an activity profile developed for the individual known active PAHs. Animals other than mice and rats should be used to examine PAH metabolite-DNA adduct formation and the mechanisms by which phenolic antioxidants and inducers of aryl hydrocarbon hydroxylase (AHH)
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and ratings of carcinogenic activity; these ratings indicate only relative activity. The third table lists nitroarenes that have been detected in particulate extracts of diesel exhaust, and the fourth shows their structural formulas.
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TABLE A- 1 Polycyclic Aromatic Hydrocarbons and Related Compounds: 1\Iolecular Formulas and CAS Numbers Name Molecular Formula CAS No.
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Dibenz~a,c~anthracene see Benzotb~triphenylene Dibenz~a,h~anthracene C22H14 53-07-3 D~benz~a,J] anthracene C22H14 224-41-9 7H-Dibenzota,gicarbazole C20H13 207-84-1 13H-Dibenzo~a,iicarbazole C20H13 239-64-5 7H-Dibenzotc,gicarbazole C20H13 194-59-2 Dibenzo~b,defichrysene C24H14 189-64-0 Dibenzo~def,mnoichrysene C22H.12 191-26-4 Dibenzo~def,p~chrysene C24H14 191-30-0 Dibenzotb,h~phenanthrene see Pentaphene Dibenzo~a,e~pyrene see Naphthot1,2,3,4-def~chrysene Dibenzota,h~pyrene see Dibenzotb,def~chrysene Dibenzota,i~pyrene see Benzotrst~pentaphene Dibenzota,l~pyrene see Dibenzo~def,p~chrysene Dibenzothiophene C12H8S 132-65-0 Fluoranthene C16Hlo 206-44-0 9H-Fluorene C13H10 86-73-7 9H-Fluoren-9-one C13H8° 484-25-9 Indenot1,2,3-cd~pyrene C22H12 - 193-39-5 lH-Indole C8H7N 120-72-9 Isoquinoline CgH7N 119-65-3 Naphthacene C18H12 92-24-0 Naphthalene ClOH8 ~ 91-20-3 Naphthot1,2, 3,4-clef ~ chrysene C24H14 192-65-4 Naphtho[2, 3-f ~ quinol ine C17Hll 224-98-6 Pentaphene C22H14 222-93-5 Perylene C20H12 198-55-0 lH-Phenalene C13H10 203-80-5 Phenanthraquinone see 9,10-Phenanthrenedione Phenanthrene C14H10 85-01-8 9,10-Phenanthrenedione C14HgO2 84-11-7 Phenanthridine C13HgN 229-87-8 1,10-Phenanthroline C12HgN2 66-71-7 Phenanthrot4,5-bcd~thiophene C14HgS 30796-92-0 Phenazine C12HgN2 92-82-0 Phenazone see Benzotcicinnoline Picene C22H14 213-46-7 Pyrene C16Hlo 129-00-0 Quinoline CgH7N 91-22-5 Triphenylene C18H12 217-59-4 9H-Xanthene C13HloO 92-83-1 A-3 ~;
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TABLE A-2 Polycyclic Aromatic Hydrocarbons and Related Compounds: Structural Formulas, Molecular Weights, and Carcinogenic Activity Structural Formula Name Molecular Carcinogenic Weight Activitya 7 H lH-Indole 117.0578 0 4 8 1 6~13 Quinoline 129.0578 5 4 8 1 7X12 Isoquinoline ~ 129.0578 0 5 4 8 1 6W~J3 Naphthalene 128.0626 0 !
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