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Possible Long-Term Health Effects of Short-Term Exposure to Chemical Agents Volume 1 (1982) / Chapter Skim
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Appendix E: Case-File Data on Edgewood Subjects
Pages 103-108

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From page 103...
... 3 sub feces Percutaneous (5.0 - 45 ug/kg) lO subjects The vast mad ority of these sub jects reportedly experienced little or no effect from the drug.
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From page 104...
... No complaints or severe effects reportedly were observer in any of the aubjecta tested by this route at the doses used. Two of the aubJecta who received GD by the intravenous route, although treated with oxide and/or atropine showed aignlficant decrease In ' the ChE levels, and exhibited the "usual physiological reaponaea" from this agent.
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From page 105...
... Intravenous ( 1.15 ug/kg ~ PAMCl ~ ~ sub jec t _ ~ ~ Scopolamine) 2 sub jects Sub jects wi th large doses experienced a rapid, severe depre ssion of RBC ChE following agent administration.
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From page 106...
... 1 sub ject doses of BZ and were subsequently treated with physostigo~ne, showed any prolonged central effects (hallucinations, disorientation, confusion) lasting 4 to 6 days post~exposure.
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From page 107...
... SUMMARY OF VOLUNTEER TESTING WITH MALATHION (A14) A total of lO sub Jects was tested witch l.~% malathion powder dusted over the entire body for up to lO days.
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From page 108...
... Although these subjects were tested or treated with several of these drugs, as well as mecholyl, their vital signs reportedly returned to normal and they were all in good condition by the end of the testing period. There were no prolonged or delayed effects from thi s drug re port ed in these subjects .
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Key Terms

  • volunteer testing
  • sub ject
  • sub jec
  • various conditions
  • che levels

  • following cri
  • blurred vision
  • esophageal motility
  • jects reportedly
  • motility studies

  • representing approximately
  • rbc che
  • multiple doses
  • reportedly experienced
  • appeared normal

  • subjects oral
  • multiple dose
  • various test
  • usual physiological
  • approximately lox

  • disclosed marked
  • stomach pain
  • observation ant
  • respiratory rate
  • reed hospital

  • jects fell
  • cri teria
  • walter reed
  • approaching normal
  • increased calibration


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