Possible Long-Term Health Effects of Short-Term Exposure to Chemical Agents Volume 1 (1982) / Chapter Skim
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Appendix G: Summary of Acute- and Chronic-Toxicity Data in Various Mammalian Species (Ditran, Benactyzine, EA 2545, EA 3167, EA 3443, EA 3392, EA 3580, EA 3834, 226,086)-- by Leo G. Abood, Ph.D.
Appendix G: Summary of Acute- and Chronic-Toxicity Data in Various Mammalian Species (Ditran, Benactyzine, EA 2545, EA 3167, EA 3443, EA 3392, EA 3580, EA 3834, 226,086)-- by Leo G. Abood, Ph.D.
Pages 111-112
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OTHER DRUGS Acute- and chronic-toxicity tests were performed by various qualified laboratories at Edgewood laboratories on the various test agents used in the Edgewood study in human volunteers. Acute toxicity was usually studied in mice, rats, cats, dogs, and monkeys to determine the LD50 and to observe pharmacologic effects, such as autonomic changes, changes in motor activity, ataxia, pros Oration, and convulsions.
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From page 112... ...
Occasionally, at nearly lethal doses, sI1ght changes were observed in the weights of some organs -- liver , heart, spleen, and thrum . There were also slight changes in blood cells (e.g., increased leukocyte county)
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