Skip to main content

Biologic Markers in Reproductive Toxicology (1989) / Chapter Skim
Currently Skimming:

29. Conclusions and Recommendations
Pages 303-310

The Chapter Skim interface presents what we've algorithmically identified as the most significant single chunk of text within every page in the chapter.
Select key terms on the right to highlight them within pages of the chapter.


From page 303...
... MODELS OF NEURODEVELOPMENT Attempts to develop mechanistic models of postnatal behavior require understanding of the development of the central nervous system and of how its components respond to a toxic insult. Radiation is useful for assessing perinatal toxicity.
Read the entire page →
From page 304...
... Nervous System-Endocrine Interactions Neural signals processed through the hypothalamus control the release of gonadotropins that regulate pituitary release of luteinizing hormone (LH) and folliclestimulating hormone (FSH)
Read the entire page →
From page 305...
... . Chemical signals can be directly measured as concentrations of gonadotropins and gonadal hormones in blood and indirectly measured by secondary physiologic events (for instance, ovulation, luteinizing-hormone releasing hormone surge, and lactation)
Read the entire page →
From page 306...
... has provided vast improvements in visualizing structures of organs in the body. CAT scanning has been heavily used in neuropsychiatric disease, and its ability to reveal structural abnormalities in the brains of schizophrenics is among the many accomplishments of these new techniques (Zec NEURODEVELOPMENTAL TOXICOLOGY and Weinberger, 1986)
Read the entire page →
From page 307...
... Red cells also absorb choline by processes somewhat similar to those in neurons (Houck et al., 1988~. Red cell choline uptake has been studied in patients with disorders thought to involve deficits in central nervous system cholinergic function, such as Alzheimer's disease.
Read the entire page →
From page 309...
... Appendix
Read the entire page →

Key Terms

  • central nervous
  • low specificity
  • neurodevelopmental toxicology
  • red cell
  • energy state

  • cell cholinesterase
  • hypothalamic dopaminergic
  • cat scanning
  • low sensitivity
  • red cells

  • positron emission
  • hormone surge
  • cholinergic function
  • neuron action
  • neurochemistry involving

  • quantitative interpretation
  • reveal structural
  • various toxicants
  • regulate pituitary
  • absorb choline

  • drug response
  • involving changes
  • luteinizing hormone
  • spin resonance
  • vast improvements

  • brain tissue
  • positrons emitted
  • yield useful
  • assess biologic
  • toxic exposures


    • This material may be derived from roughly machine-read images, and so is provided only to facilitate research.
    More information on Chapter Skim is available.