Health Effects of Permethrin-Impregnated Army Battle-Dress Uniforms (1994) / Chapter Skim
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APPENDIX A
APPENDIX A
Pages 129-137
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Appendix A
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. A risk assessment is an attempt to describe potential health risks resulting from specific exposure scenario to a given contaminant.
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A key toxicity value in quantifying potential carcinogenic risk is the carcinogen potency factor. This value represents the slope of the upper 95 % confidence interval of the extrapolated dose response curve.
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A preliminary exposure assessment was previously published (reference 6~. The predicted exposure of approximately 0.005 mg/kg/day was based on continuous wear of a uniform impregnated with permethrin at a target concentration of 0.125 mg/cm2.
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(g) Daily Wear - 16 hrs / day While soldiers may sleep in clothing, 16 hours per day is the maximum predicted contact time when averaged over a 6-year exposure period.
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x (1.6 x 10-2 mg/kg/day) =6 x 10-7 This value represents an upper bound estimate of carcinogenic risk under the exposure conditions outlined above.
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Our potency factor derivation is also based on summaries of animal data and not the original literature. We were forced to estimate animal dose levels based on estimated body weights and food consumption rates.
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Interim Report on Contract for Further Investigation of the Application of Permethrin to Battle Dress Uniforms, MER Report No. 886S, NRDEC Technical Report.
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