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10 The World Wide Laboratory: Remote and Automated Access to Imaging Instrumentation
Pages 141-153

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From page 141...
... In the service mode, a local operator can consult with a remotely located principal researcher providing a specimen and who would provide input about the quality of the images and the parameters to be used to acquire data. This mode is extremely important for extending service capabilities at the National Research Resources.
From page 142...
... These servers are responsible for controlling the TEM and digital camera using applications and libraries already developed as part of the emScope library.3 The user interface is shown in Figure 10.2. As a readily accessible tool for remote consultation and exploratory grid browsing, the basic Javascope implementation has been successful.
From page 143...
... The NSCOPE was initially developed to support functional magnetic resonance imaging and dynamic imaging applications. The modular software architecture of the system has allowed us to adapt the system to other user interfaces.
From page 144...
... and microscope control (right)
From page 145...
... THE WORLD WIDE LABORATORY: REMOTE AND AUTOMATED ACCESS TO IMAGING INSTRUMENTATION 145 FIGURE 10.3 Web-based control system provides interactive access to all imaging parameters on the MRI system.
From page 146...
... The Web browser interface allows users from various domains and levels of expertise to run the MRI system without the need for extensive system-specific training. Chickscope: A K-12 Education Project Using Remote MRI The remote MRI system was used in the spring of 1996 in a project called Chickscope,7 ~ which demonstrated the feasibility of remotely controlling an MRI device through the World Wide Web.
From page 147...
... Automated/Intelligent Control for Scientific Research Our croup has been extensively involved in a Project involving scientific research on remote and ~, automated instrumentation. The goal of the project is to acquire very large numbers of good-quality images from a TEM completely unattended by a human operator.
From page 148...
... Acquiring good-quality images of this specimen is often used as a test for students taking a course in electron microscopy and thus provides an excellent driver for the research methods that must be developed to solve the general problems of automated image acquisition. Furthermore, as catalase is an ordered crystalline structure, assessment of this order provides us with an objective measure of the quality of the automatically acquired images (Figure 10.5)
From page 149...
... This feature intensity is related to the thickness of the catalase crystal and indicates that thinner specimens result in more acceptable images. The fully automated target selection criteria were further refined by incorporating an assessment of specimen thickness into the model.
From page 150...
... complicated by the lack of open systems and industry standards. Ideally the instrument should require minimal human interaction during an automated experiment.
From page 151...
... Although the Chickscope project was not originally intended to do so, we believe in retrospect that this project demonstrated all of the components defined for a working collaborators. Chickscope provided access to remote instrumentation from the classroom and gave students access to distributed expertise.
From page 152...
... One of the lessons learned from the Chickscope project was that the second graders thought this was entirely natural: Why shouldn't they have an MRI? Why shouldn't they be speaking to researchers from all over the world and accessing thousands of images?
From page 153...
... And certainly really decent electron microscopes these days cost $1.5 million to $2 million each. You are not going to have more than a dozen or so of those in the country.


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