The Five Series Study Mortality of Military Participants in U.S. Nuclear Weapons Tests (2000) / Chapter Skim
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1 Study Rationale and Overview
1 Study Rationale and Overview
Pages 5-7
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From page 5... ...
This study, however, does not address questions concerning the relationships between test participation or radiation exposure and nonfatal adverse health effects. BACKGROUND In 1976, a veteran asserted that his acute myelocytic leukemia was related to his participation in Shot SMOKY, a test in the 1957 Operation PLUMBBOB series at the Nevada Test Site.
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From page 6... ...
In July 1992, the Institute of Medicine established an eight-member committee representing expertise in epidemiology, biostatistics, radiation biology, radiation medicine, military records, and health physics to advise MFUA staff. This committee provided oversight concerning methods of exposure-data ascertainment, mortality assessment, referent group selection, radiation effects on human health, consideration of carcinogenesis mechanisms, statistical methods, and military records use.
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From page 7... ...
Additional analytic work involved the use of more detailed, though still broad, cause-of-death categories and the exploration of characteristics of the participation experience for evidence consistent with a radiationcaused effect (see Chapter 11~. Initial plans to examine dose-response relationships were changed when a working group2 formed by the study's advisory committee determined that the available dose data were inappropriate for use in individual-level epidemiologic analyses (see Chapter 7 and Appendix A)
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