Graduate Education in the Chemical Sciences Issues for the 21st Century: Report of a Workshop (2000) / Chapter Skim
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14 Training Grants in the Chemical and Biological Sciences
14 Training Grants in the Chemical and Biological Sciences
Pages 144-158
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From page 144... ...
While depth of knowledge and experience in a particular field is still the most important component of good graduate education, students also must acquire scientific breadth and the interpersonal skills necessary to function as a team member. In the 1980s and 1990s, academic units in the biological and pharmaceutical sciences recognized the need to change and effectively used predoctoral training grants provided by the National Institutes of Health (NIH)
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From page 145... ...
Professor Higuchi, who was trained as a physical chemist, entered the field of pharmaceutical chemistry in the late 1940s when he joined the faculty of the School of Pharmacy at the University of Wisconsin. After moving to the University of Kansas, Professor Higuchi built the predoctoral training and research programs in the Department of Pharmaceutical Chemistry around the philosophy that success in understanding drug actions, controlling drug delivery across biological barriers and to drug receptors, developing stable drug formulations, and creating methods for analysis of drug substances required a thorough knowledge of the basic principles of analytical, physical, physical organic, and organic chemistry.
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From page 146... ...
and/or because they could serve as mentors for trainees during their industrial internships. To facilitate the development of this multidisciplinary program in pharmaceutical biotechnology, the University of Kansas successfully competed for a predoctoral training grant from the National Institute of General Medical Sciences (NIGMS)
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From page 147... ...
147 / This multidisciplinary training program in pharmaceutical biotechnology has as its primary objective "the training of pharmaceutical scientists who have the expertise to assist in the preclinical and clinical discovery/development of macromolecule-based drug candidates." The program is administered by a steering committee composed of faculty representatives from the participating academic units (i.e., Departments of Pharmaceutical Chemistry, Chemistry, Molecular Biosciences, and Chemical Engineer
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From page 148... ...
degrees are awarded in these disciplines. However, as trainees in the Pharmaceutical Biotechnology Program, the students also must complete several additional requirements, including completion of "core" courses and courses in their area of specialization, participation in a biotechnology seminar and a biotechnology journal club, and completion of an industrial internship.
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From page 149... ...
Trainees in the Pharmaceutical Biotechnology Program are required to complete three "core" courses, one of which is in molecular biology. From this course, the students learn the language of this discipline, which helps them function effectively in multidisciplinary drug discovery development teams in biotechnology companies.
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From page 150... ...
To facilitate communication among the trainees and the faculty members and to ensure exposure of the trainees to the external scientific community, the students participate in a monthly seminar series entitled "Pharmaceutical Aspects of Biotechnology." Many of the seminar speakers are scientists from biotechnology and major pharmaceutical companies. These individuals provide the students with practical examples of the development of macromolecules as drug candidates.
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From page 151... ...
· Pharmaceutical scientists today must be broadly trained so that they can communicate with scientists in other disciplines and work effectively on project teams. · Training grants provide an excellent mechanism to facilitate change in academic programs and to guild multidisciplinary training programs that can expand the scientific breadth of the students as well as enrich their scientific depth.
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From page 152... ...
RELATED READING Ronald T Borchardt, "Are Graduate Programs Training Pharmaceutical Scientists to Function Effectively in the New, Highly Integrated and Globalized Pharmaceutical Industry?
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From page 153... ...
Korchardt: Let me begin by saying that we have a number of training grants at the University of Kansas, each in a different area. My presentation focused on the training grant in pharmaceutical biotechnology with the "core' department for this training grant being pharmaceutical chemistry.
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From page 154... ...
Ronald T Borchardt: I find that graduates of chemistry departments are in general very, very bright, and they quickly learn what is important in the pharmaceutical industry.
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From page 155... ...
This supplement is used to cover living expenses while the student is completing the internship. Victor Vandell, Louisiana State University: I am a proponent of multidisciplinary training, and I am also a product of that, as my background is in organic and analytical chemistry.
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From page 156... ...
The other 70 percent comes from industry. Clearly, the pharmaceutical industry is an important contributor to the gross domestic product, but it is only a fraction of the total chemical manufacturing contribution.
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From page 157... ...
So, I think your question is probably more appropriately directed to the representatives of the chemistry departments in the audience. Robert Humphreys: I want to pick up a little on what Ron said, particularly with respect to the idea of having a strategic plan.
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From page 158... ...
In looking around the room, I have noticed that there are about a dozen universities in this country that have well-known chemistry departments that are not represented. I agree that one of the important functions of a university is to serve the student, and serving the student includes preparing him or her for a job.
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