A significant medical event is expected in 1992: the first human use of a fully implantable, long-term cardiac assist device. This timely volume reviews the artificial heart program--and in particular, the National Institutes of Health's major investment--raising important questions.
The volume includes:
Consideration of the artificial heart versus heart transplantation and other approaches to treating end-stage heart disease, keeping in mind the different outcomes and costs of these treatments.
A look at human issues, including the number of people who may require the art
The very rapid pace of advances in biomedical research promises us a wide range of new drugs, medical devices, and clinical procedures. The extent to which these discoveries will benefit the public, however, depends in large part on the methods we choose for developing and testing them.
Modern Methods of Clinical Investigation focuses on strategies for clinical evaluation and their role in uncovering the actual benefits and risks of medical innovation.
Essays explore differences in our current systems for evaluating drugs, medical devices, and clinical procedures; health insurance
One of a continuing series on Frontiers of Visual Science, this short volume contains papers presented at a recent symposium. These papers describe techniques for assessing the structure and function of photoreception, both in isolation and in aggregation as the "receptor mosaic" of the retina. Also described are dynamic and spatial sampling properties of photoreceptors, with an emphasis on techniques of measurement and associated models of retinal function.
This volume should be of interest to basic vision scientists, clinical ophthalmologists, workers in human factors, and computer scient
Biomedical scientists' concern about the future of funding of health science research prompted this volume's exploration of the financing of the entire health research enterprise and the complex reasons underlying these increasing concerns. The committee presents clear-cut recommendations for improving allocation policies to ensure a balanced distribution of resources that will allow the biomedical research community to build on exciting recent discoveries in many areas. Funding Health Sciences Research also provides the first-ever comprehensive reports on the 1980s policies that have a
Biologic markers--indicators of biological exposure or change--offer the promise of early detection of disease caused by environmental exposure. Researchers have used these markers to discover indications of pulmonary damage from low-level ozone, a finding with serious implications for health professionals and environmental regulators. Biologic Markers in Pulmonary Toxicology is a comprehensive study of this use of biologic markers. Focusing on the respiratory tract as an entryway for airborne pollutants, this volume reviews new ways of measuring markers, the need for markers to indicat
This book results from a study by a committee of the Institute of Medicine and the National Research Council's Board on Agriculture. The committee examined the scientific foundations of medically assisted conception and developed an agenda for basic research in reproductive and developmental biology that would contribute to advances in the clinical and agricultural practice of in vitro fertilization and embryo transfer. The volume also discusses some barriers to progress in research and ways of lowering them, and explains the scientific issues important to ethical decision making.
Recent vision research has led to the emergence of new techniques that offer exciting potential for a more complete assessment of vision in clinical, industrial, and military settings. Emergent Techniques for Assessment of Visual Performance examines four areas of vision testing that offer potential for improved assessment of visual capability including: contrast sensitivity function, dark-focus of accommodation, dynamic visual acuity and dynamic depth tracking, and ambient and focal vision. In contrast to studies of accepted practices, this report focuses on emerging te