Definition of Pain and Distress and Reporting Requirements for Laboratory Animals: Proceedings of the Workshop Held June 22, 2000

National Research Council

doi:10.17226/10035

Definition of Pain and Distress and Reporting Requirements for Laboratory Animals: Proceedings of the Workshop Held June 22, 2000 (2000)

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Definition of Pain and Distress and Reporting Requirements for Laboratory Animals

Proceedings of the Workshop Held June 22, 2000 (2000)

Proceedings

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Overview

Contributors

National Research Council; Institute for Laboratory Animal Research; Committee on Regulatory Issues in Animal Care and Use

Description

In this first in a proposed series of workshops on regulatory issues in animal care and use, the Institute for Laboratory Animal Research (ILAR) has addressed the existing and proposed requirements for reporting pain and distress in laboratory animals. The Animal Welfare Act, administered by the Animal and Plant Health Inspection Service of the United States Department of Agriculture (USDA), mandates that pain and distress in laboratory animals be minimized. USDA is considering two policy changes with regard to this specific mandate. Firstly, since there has been no functional definition of "distress," USDA has prepared such a definition and requested feedback from the scientific community on its usefulness for regulatory and reporting requirements.

The second issue concerns the pain and distress categorization scheme for reporting to USDA. Various groups and individuals have questioned the efficacy of the current categories, and specific changes have been proposed by the Humane Society of the United States. USDA is considering these and other potential changes to the existing scheme. Thus, given these potential changes to animal welfare policy, the aim of the ILAR/NIH joint workshop was to provide feedback to the USDA. The speakers were asked to address these two issues as well as to comment upon whether the information contained in the 1992 ILAR report Recognition and Alleviation of Pain and Distress in Laboratory Animals is still useful to investigators in assisting them to comply with regulations. The speakers provided perspectives based on their individual expertise in the areas of science of pain and distress, animal welfare policy, protocol review, and/or as representatives of relevant organizations or institutions. The following proceedings are an edited transcript of their presentations.

Topics

Biology and Life Sciences — Laboratory Animal Research

Suggested Citation

National Research Council. 2000. Definition of Pain and Distress and Reporting Requirements for Laboratory Animals: Proceedings of the Workshop Held June 22, 2000. Washington, DC: The National Academies Press. https://doi.org/10.17226/10035.

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Publication Info

131 pages | 6 x 9
ISBNs:

Paperback: 978-0-309-07291-5
Ebook: 978-0-309-17128-1

DOI: https://doi.org/10.17226/10035

RESOURCES AT A GLANCE

Press Release

Contents

Table of Contents	skim chapter
Front Matter	i-xii
Introduction	1-2
Pain and Distress: USDA Perspective	3-8
Pain, Distress, and Reporting Requirements: PHS Policy Perspective	9-12
Assessing Pain and Distress: A Veterinary Behaviorist's Perspective	13-21
Scientific Issues of Pain and Distress	22-30
The Humane Society of the United States Pain and Distress Initiative	31-36
Pain and Distress Caused by Experimental Procedures--Is It Time for a Reality Check?	37-43
A View from the Trenches	44-52
AALAS Position Paper on the 'Recognition and Alleviation of Pain and Distress in Laboratory Animals'	53-57
On Regulating Pain and Distress	58-62
An Industrial Perspective	63-70
Corners Still Unswept	71-76
Personal Experiences with Clinical Pain Management, Study Design, Mitigation of Scientific Cofounders, and Long-term Gains to the Researchers and Public	77-81
Use of Laboratory Animals in the Postgenome Era	82-86
The History and Histrionics of Pain and Distress in Laboratory Animals	87-92
Panel Discussion with All Speakers	93-98
Appendix A: APHIS/USDA Policy 11 and Policy 12	99-103
Appendix B: Proposed Rulemaking	104-111
Appendix C: Glossary of Abbreviations	112-112
Appendix D: Meeting Participants	113-114
Appendix E: Meeting Agenda	115-117
Appendix F: Biographical Sketches of Committee Members	118-119

Resources

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