The Global Crisis of Drug-Resistant Tuberculosis and Leadership of China and the BRICS: Challenges and Opportunities: Summary of a Joint Workshop by the Institute of Medicine and the Institute of Microbiology, Chinese Academy of Sciences

Institute of Medicine

doi:10.17226/18346

The Global Crisis of Drug-Resistant Tuberculosis and Leadership of China and the BRICS : Challenges and Opportunities: Summary of a Joint Workshop by the Institute of Medicine and the Institute of Microbiology, Chinese Academy of Sciences (2014)

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The Global Crisis of Drug-Resistant Tuberculosis and Leadership of China and the BRICS

Challenges and Opportunities: Summary of a Joint Workshop by the Institute of Medicine and the Institute of Microbiology, Chinese Academy of Sciences (2014)

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Overview

Contributors

Institute of Medicine; Board on Health Sciences Policy; Forum on Drug Discovery, Development, and Translation; Steve Olson, Rebecca A. English, and Anne B. Claiborne, Rapporteurs

Description

Multidrug-resistant tuberculosis (TB) is caused by bacteria resistant to isoniazid and rifampicin, the two most effective first-line anti-TB drugs, originally developed and introduced in the 1950 and 1960s. Since 2008, the Forum on Drug Discovery, Development, and Translation of the Institute of Medicine has hosted or co-hosted six domestic and international workshops addressing the global crisis of drug-resistant TB, with special attention to the BRICS countries - Brazil, Russia, India, China, and South Africa.

The Global Crisis of Drug-Resistant Tuberculosis and Leadership of China and the BRICS is the summary of a workshop convened to address the current status of drug-resistant TB globally and in China. This report considers lessons learned from high burden countries; highlights global challenges to controlling the spread of drug-resistant strains; and discusses innovative strategies to advance and harmonize local and international efforts to prevent and treat drug-resistant TB. Additionally, the report examines the problem of MDR TB and emergent TB strains that are potentially untreatable with drugs available and considers the critical leadership role of the BRICS countries in addressing the threats and opportunities in drug-resistant TB.

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Suggested Citation

Institute of Medicine. 2014. The Global Crisis of Drug-Resistant Tuberculosis and Leadership of China and the BRICS: Challenges and Opportunities: Summary of a Joint Workshop by the Institute of Medicine and the Institute of Microbiology, Chinese Academy of Sciences. Washington, DC: The National Academies Press. https://doi.org/10.17226/18346.

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Publication Info

218 pages | 6 x 9
ISBNs:

Paperback: 978-0-309-28596-4
Ebook: 978-0-309-28599-5

DOI: https://doi.org/10.17226/18346

Contents

Table of Contents	skim chapter
Front Matter	i-xxii
1 Introduction and Overview of the Workshop	1-10
2 The Challenges and Opportunities for the BRICS Countries to Lead	11-22
3 Catching Up with the Microbe	23-30
4 Drug-Resistant TB in China	31-44
5 Experiences with MDR TB in Other Countries	45-54
6 Drug-Resistant Tuberculosis in Pediatric Populations	55-62
7 Global Perspectives on Transmission and Infection Control	63-78
8 Rapid Diagnostic Technologies: Status and Limitations	79-90
9 Addressing Diagnosis and Treatment Across the Spectrum of Drug Resistance	91-108
10 Developing and Strengthening the Drug Supply Chain for Drug-Resistant TB	109-118
11 Embracing a New Vision for Research	119-128
12 What Will Be Required to Achieve Zero Deaths from TB?	129-136
13 Creating an Evidence-Based Blueprint for Action	137-142
References	143-150
Appendix A: Workshop Agenda	151-170
Appendix B: Participant Biographies	171-196

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