Millions of Americans use e-cigarettes. Despite their popularity, little is known about their health effects. Some suggest that e-cigarettes likely confer lower risk compared to combustible tobacco cigarettes, because they do not expose users to toxicants produced through combustion. Proponents of e-cigarette use also tout the potential benefits of e-cigarettes as devices that could help combustible tobacco cigarette smokers to quit and thereby reduce tobacco-related health risks. Others are concerned about the exposure to potentially toxic substances contained in e-cigarette emissions, especially in individuals who have never used tobacco products such as youth and young adults. Given their relatively recent introduction, there has been little time for a scientific body of evidence to develop on the health effects of e-cigarettes.
Public Health Consequences of E-Cigarettes reviews and critically assesses the state of the emerging evidence about e-cigarettes and health. This report makes recommendations for the improvement of this research and highlights gaps that are a priority for future research.
Table of Contents
|2 Committee Approach||35-42|
|Section I E-Cigarette Devices, Constituents, and Exposures||43-44|
|3 E-Cigarette Devices, Uses, and Exposures||45-70|
|5 Toxicology of E-Cigarette Constituents||123-172|
|6 Research Needs: E-Cigarette Devices, Constituents, and Exposures||173-176|
|Section II Effects of E-Cigarettes on Health||177-178|
|7 Modes of Action||179-204|
|8 Dependence and Abuse Liability||205-262|
|9 Cardiovascular Disease||263-296|
|11 Respiratory Diseases||319-356|
|12 Oral Diseases||357-362|
|13 Developmental and Reproductive Effects||363-372|
|14 Injuries and Poisonings||373-378|
|15 Research Needs: Effects of E-Cigarettes on Health||379-382|
|Section III Public Health Implications of E-Cigarettes||383-386|
|16 Combustible Tobacco Cigarette Smoking Among Youth and Young Adults||387-422|
|17 Smoking Cessation Among Adults||423-462|
|18 Harm Reduction||463-496|
|19 Modeling of E-Cigarette Use||497-514|
|20 Research Needs: Public Health Implications of E-Cigarettes||515-518|
|21 Concluding Observations||519-522|
|Appendix A Questions from the Center for Tobacco Products of the Food and Drug Administration Submitted for the Committee's Consideration||523-526|
|Appendix B Search Strategy and Quality Assessment||527-552|
|Appendix C Glossary of Terms Related to E-Cigarettes||553-556|
|Appendix D Cytotoxicity Tables||557-584|
|Appendix E Public Meeting Agenda||585-586|
|Appendix F Committee Biosketches||587-590|
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