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Appendix WORK OF THE COMMITTEE To conduct this study, the Institute of Medicine established a committee of experts drawn from relevant disciplines, including clinical medicine, epidemiology, pharmacology, psychiatry, and toxicology. This steering committee's expertise was augmented by consultants, as well as by many other persons serving as panel members. Six panels, each chaired by a committee member, were formed to carry out a detailed analysis of such special issues as the effects of cannabis use on behavioral and psychosocial development, on reproductive and fetal biology, on cardiovascular and respiratory systems, and to consider neurobiologic, genetic, oncogenic, and cytogenetic issues, and cell biology, including pharmacologic and immunologic aspects. During the early months of the study, the panels met to apportion writing responsibilities, and established the scope and focus of each panel's undertaking. The chronology of the panel meetings follows. February 3, l98l: Panel on Behavioral and Psychosocial Issues met in Washington February l8, l98l: Panel on Neurobiological Issues met in Washington February 26, l98l: Panel on Cardiovascular and Respiratory Issues met in New York City February 27, l98l: Panel on Genetic/Oncogenic/Cytogenetic Issues met in Washington March ll, l98l: Panel on Reproductive and Fetal Issues met in Boston March l6, l98l: Subpanel on Intrapersonal Variables and Social Behavior of the Panel on Behavioral and Psychosocial Issues met in Los Angeles March 23, l98l: Panel on Cell Biology/Pharmacological and Immunological Issues met in Boston April l4, l98l: Panel on Behavioral and Psychosocial Issues met in Washington The steering committee, in the meantime, nominated additional candidates for membership on the panels and committee at its first meeting on December l, l980. Subsequently, four more meetings were l69
l68 than it has apparently received to date. A drug that is currently used by about a third of all American high school seniors, and daily by about one in eleven, deserves more study than we currently are giving it. No other illicit drug is used as widely by our youth, and yet NIDA spent only 9 percent of its research budget on it in FY '80. â¢ NIDA would be advised to continue its recent policy of reducing the relative proportion of contracts and emphasizing grants. Although we believe that there is need for federal initiatives in stimulating work in neglected areas of current concern, the bulk of research supert should continue to go to investigator-initiated projects. â¢ The duration for investigator-initiated research should be lengthened beyond the average 3-year period in order to attract and hold good researchers. â¢ Other agencies should contribute funds for the production, processing, and distribution of cannabis. â¢ A scientific advisory group should be formed to assist in providing scientific evidence and guidance to the director of NIDA. â¢ An increased interagency effort targeted toward specific problems not readily addressed by other approaches is required. These would include, for example, human long-term studies, as well as studies in epidemiology, prevention, and treatment. Funds should be contributed by all agencies. ' Research on human beings and other primates should be encouraged, particularly studies in the young. There is a special need at this time for good epidemiological studies that follow identifiable cohorts of marijuana users over a period of time. REFERENCES Hurd, Susan. National Heart, Lung, and Blood Institute. Bethesda, Md. Personal communication, l98l. Little, Francine. National Cancer Institute, Bethesda, Md. Personal communication, l98l. Leventhal, Carl. National Institute of Arthritis, Metabolism, and Digestive Diseases, Bethesda, Md. Personal communication, l98l. Ludford, Jacqueline. National Institute on Drug Abuse, Rockville, MD. Personal communication, l98l. Petersen, Robert. National Institute on Drug Abuse, Rockville, Md. Personal communication, l98l. Pollin, W. Statement on Drug Abuse Research before the Subcommittee on Alcoholism and Drug Abuse, Committee on Labor and Human Resources. United States Senate, July 27, l98l. Snyder, Marvin. National Institute on Drug Abuse, Bethesda, Md. Personal communication, l98l.