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Suggested Citation:"Appendix B: Workshop Agenda." National Academies of Sciences, Engineering, and Medicine. 2019. Improving Cancer Diagnosis and Care: Clinical Application of Computational Methods in Precision Oncology: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/25404.
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Appendix B
Workshop Agenda

OCTOBER 29, 2018

7:30 am Registration
8:00 am Welcome from the National Cancer Policy Forum and the Board on Mathematical Sciences and Analytics
Christopher Cogle, University of Florida
Chair, Workshop Planning Committee
David Chu, Institute for Defense Analyses
Member, Board on Mathematical Sciences and Analytics
8:15 am Session 1: Workshop Overview
Moderator: Hedvig Hricak, Memorial Sloan Kettering Cancer Center
Precision Oncology: The Optimism and Pessimism from Keyboard to Bedside
  • Christopher Cogle, University of Florida
Brief Review of Improving Cancer Diagnosis and Care: Patient Access to Oncologic Imaging and Pathology Expertise and Technologies (February 2018, National Cancer Policy Forum Workshop)
  • Hedvig Hricak, Memorial Sloan Kettering Cancer Center
Suggested Citation:"Appendix B: Workshop Agenda." National Academies of Sciences, Engineering, and Medicine. 2019. Improving Cancer Diagnosis and Care: Clinical Application of Computational Methods in Precision Oncology: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/25404.
×
Keynote: A Roadmap for Translating Precision Oncology into Clinical Practice
  • Atul Butte, University of California, San Francisco
Panel Discussion
10:10 am Break
10:15 am Session 2: Defining Unmet Needs and Challenges of Precision Oncology in Clinical Practice
Moderator: Christopher Cogle, University of Florida
High-Dimensional Data in Precision Oncology: Signal and Hype
  • Constantine Gatsonis, Brown University
Biologic and Metaphysical Limits to Pursuing Precision Oncology
  • Keith Flaherty, Massachusetts General Hospital
The Risks of Bias and Inequities in Precision Oncology Care
  • Kadija Ferryman, Data & Society Research Institute
Communication Challenges in Precision Oncology
  • Galen Joseph, University of California, San Francisco
Panel Discussion
12:15 pm Lunch
1:00 pm Session 3: Data Considerations for Precision Oncology Care
Moderator: Amy Abernethy, Flatiron Health
Envisioning Critical Features of Datasets for Precision Oncology Care
  • Amy Abernethy, Flatiron Health
Opportunities and Lessons Learned from AACR’s Project GENIE
  • Mia Levy, Vanderbilt University
Suggested Citation:"Appendix B: Workshop Agenda." National Academies of Sciences, Engineering, and Medicine. 2019. Improving Cancer Diagnosis and Care: Clinical Application of Computational Methods in Precision Oncology: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/25404.
×
Data Standardization and Harmonization
  • Sean Khozin, Food and Drug Administration
Data Governance, Privacy, and Security
  • Deven McGraw, Ciitizen
Panel Discussion
Includes speakers and
  • David Magnus, Stanford University
3:00 pm Break
3:15 pm Session 4: Analysis and Interpretation of Computational Methods for Precision Oncology Care
Moderator: Constantine Gatsonis, Brown University
Conceptual Strategies for Reproducibility of Precision Oncology Data and Methods
  • Steven Goodman, Stanford University School of Medicine
Validation and Replicability of Prediction Algorithms in Oncology
  • Giovanni Parmigiani, Dana-Farber Cancer Institute
Assessing Readiness of an Omics Signature for Use in a Clinical Trial
  • Lisa McShane, National Cancer Institute
Regulation and Assessment of Quantitative Imaging Tools Used in Precision Oncology
  • Nicholas Petrick, Food and Drug Administration
Digital Clinical Trials for Oncology Patients with Novel Machine Learning and Artificial Intelligence Architectures
  • Pratik Shah, Massachusetts Institute of Technology Media Lab
Panel Discussion
5:30 pm Adjourn Day 1
5:35 pm Reception
Suggested Citation:"Appendix B: Workshop Agenda." National Academies of Sciences, Engineering, and Medicine. 2019. Improving Cancer Diagnosis and Care: Clinical Application of Computational Methods in Precision Oncology: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/25404.
×

October 30, 2018

7:30 am Registration and Breakfast
8:00 am Session 5: Clinical Application of Precision Oncology: Improving the Translation of Omics Technologies in Cancer Care
Moderator: Mia Levy, Vanderbilt University
Demonstrating Clinical Utility in Cancer Patient Management
  • Lincoln Nadauld, Intermountain Healthcare
Health Care Delivery Models and Infrastructure for Precision Oncology Care
  • Howard McLeod, Moffitt Cancer Center
Scaling Precision Oncology Care: Lessons Learned from Implementing Artificial Intelligence Across Health Care and Community Settings
  • George “Holt” Oliver, Parkland Center for Clinical Innovation
Health Insurance Coverage Issues
  • Lee N. Newcomer, Lee N. Newcomer Consulting
Panel Discussion
Include speakers and
  • Michael Kelley, Duke University and Veterans Health Administration
  • Lukas Amler, Genentech
10:00 am Break
10:15 am Session 6: Panel Discussion: Stakeholder Perspectives of the Path Forward
Moderator: David Magnus, Stanford University
  • Richard Schilsky, American Society of Clinical Oncology
  • Frank F. Weichold, Food and Drug Administration
  • Bray Patrick-Lake, Duke University and All of Us Research Program
  • Deven McGraw, Ciitizen
Suggested Citation:"Appendix B: Workshop Agenda." National Academies of Sciences, Engineering, and Medicine. 2019. Improving Cancer Diagnosis and Care: Clinical Application of Computational Methods in Precision Oncology: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/25404.
×
  • Lisa McShane, National Cancer Institute
  • Lee Newcomer, Lee N. Newcomer Consulting
  • Joseph Chin, Centers for Medicare & Medicaid Services
  • Lukas Amler, Genentech
11:30 am Workshop Wrap Up
Christopher Cogle, University of Florida
Chair, Workshop Planning Committee
11:45 am Adjourn
Suggested Citation:"Appendix B: Workshop Agenda." National Academies of Sciences, Engineering, and Medicine. 2019. Improving Cancer Diagnosis and Care: Clinical Application of Computational Methods in Precision Oncology: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/25404.
×

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Suggested Citation:"Appendix B: Workshop Agenda." National Academies of Sciences, Engineering, and Medicine. 2019. Improving Cancer Diagnosis and Care: Clinical Application of Computational Methods in Precision Oncology: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/25404.
×
Page 67
Suggested Citation:"Appendix B: Workshop Agenda." National Academies of Sciences, Engineering, and Medicine. 2019. Improving Cancer Diagnosis and Care: Clinical Application of Computational Methods in Precision Oncology: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/25404.
×
Page 68
Suggested Citation:"Appendix B: Workshop Agenda." National Academies of Sciences, Engineering, and Medicine. 2019. Improving Cancer Diagnosis and Care: Clinical Application of Computational Methods in Precision Oncology: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/25404.
×
Page 69
Suggested Citation:"Appendix B: Workshop Agenda." National Academies of Sciences, Engineering, and Medicine. 2019. Improving Cancer Diagnosis and Care: Clinical Application of Computational Methods in Precision Oncology: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/25404.
×
Page 70
Suggested Citation:"Appendix B: Workshop Agenda." National Academies of Sciences, Engineering, and Medicine. 2019. Improving Cancer Diagnosis and Care: Clinical Application of Computational Methods in Precision Oncology: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/25404.
×
Page 71
Suggested Citation:"Appendix B: Workshop Agenda." National Academies of Sciences, Engineering, and Medicine. 2019. Improving Cancer Diagnosis and Care: Clinical Application of Computational Methods in Precision Oncology: Proceedings of a Workshop. Washington, DC: The National Academies Press. doi: 10.17226/25404.
×
Page 72
Improving Cancer Diagnosis and Care: Clinical Application of Computational Methods in Precision Oncology: Proceedings of a Workshop Get This Book
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A hallmark of high-quality cancer care is the delivery of the right treatment to the right patient at the right time. Precision oncology therapies, which target specific genetic changes in a patient’s cancer, are changing the nature of cancer treatment by allowing clinicians to select therapies that are most likely to benefit individual patients. In current clinical practice, oncologists are increasingly formulating cancer treatment plans using results from complex laboratory and imaging tests that characterize the molecular underpinnings of an individual patient’s cancer. These molecular fingerprints can be quite complex and heterogeneous, even within a single patient. To enable these molecular tumor characterizations to effectively and safely inform cancer care, the cancer community is working to develop and validate multiparameter omics tests and imaging tests as well as software and computational methods for interpretation of the resulting datasets.

To examine opportunities to improve cancer diagnosis and care in the new precision oncology era, the National Cancer Policy Forum developed a two-workshop series. The first workshop focused on patient access to expertise and technologies in oncologic imaging and pathology and was held in February 2018. The second workshop, conducted in collaboration with the Board on Mathematical Sciences and Analytics, was held in October 2018 to examine the use of multidimensional data derived from patients with cancer, and the computational methods that analyze these data to inform cancer treatment decisions. This publication summarizes the presentations and discussions from the second workshop.

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