National Academies Press: OpenBook

Guiding Cancer Control: A Path to Transformation (2019)

Chapter: Appendix C: Disclosure of Unavoidable Conflict of Interest

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Suggested Citation:"Appendix C: Disclosure of Unavoidable Conflict of Interest." National Academies of Sciences, Engineering, and Medicine. 2019. Guiding Cancer Control: A Path to Transformation. Washington, DC: The National Academies Press. doi: 10.17226/25438.
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Appendix C

Disclosure of Unavoidable Conflict of Interest

The conflict of interest policy of the National Academies of Sciences, Engineering, and Medicine (http://www.nationalacademies.org/coi) prohibits the appointment of an individual to a committee authoring a Consensus Study Report if the individual has a conflict of interest that is relevant to the task to be performed. An exception to this prohibition is permitted if the National Academies determines that the conflict is unavoidable and the conflict is publicly disclosed. A determination of a conflict of interest for an individual is not an assessment of that individual’s actual behavior or character or ability to act objectively despite the conflicting interest.

It was determined that George Poste had a conflict of interest in relation to his service on the Committee on a National Strategy for Cancer Control in the United States because he serves on the board of directors of Exelexis, Inc., and Caris Life Sciences.

The National Academies concluded that in order for the committee to accomplish the tasks for which it was established, its membership must include at least one person with current industry experience in drugs, devices, and vaccines development. As described in his biographical summary, Dr. Poste has extensive and current experience in multiple industry sectors that focus on developing preventive, diagnostic, and therapeutic interventions for cancers.

The National Academies determined that the experience and expertise of Dr. Poste was needed for the committee to accomplish the task

Suggested Citation:"Appendix C: Disclosure of Unavoidable Conflict of Interest." National Academies of Sciences, Engineering, and Medicine. 2019. Guiding Cancer Control: A Path to Transformation. Washington, DC: The National Academies Press. doi: 10.17226/25438.
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for which it has been established. The National Academies could not find another available individual with the equivalent experience and expertise who does not have a conflict of interest. Therefore, the National Academies concluded that the conflict was unavoidable and publicly disclosed it through the National Academies Projects and Activities System (https://nationalacademies.org/pa).

Suggested Citation:"Appendix C: Disclosure of Unavoidable Conflict of Interest." National Academies of Sciences, Engineering, and Medicine. 2019. Guiding Cancer Control: A Path to Transformation. Washington, DC: The National Academies Press. doi: 10.17226/25438.
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Page 159
Suggested Citation:"Appendix C: Disclosure of Unavoidable Conflict of Interest." National Academies of Sciences, Engineering, and Medicine. 2019. Guiding Cancer Control: A Path to Transformation. Washington, DC: The National Academies Press. doi: 10.17226/25438.
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Throughout history, perhaps no other disease has generated the level of social, scientific, and political discourse or has had the degree of cultural significance as cancer. A collective in the truest sense of the word, "cancer" is a clustering of different diseases that afflict individuals in different ways. Its burdens are equally broad and diverse, from the physical, financial, and psychological tolls it imposes on individuals to the costs it inflicts upon the nation’s clinical care and public health systems, and despite decades of concerted efforts often referred to as the "war on cancer", those costs have only continued to grow over time. The causes and effects of cancer are complex—in part preventable and treatable, but also in part unknown, and perhaps even unknowable.

Guiding Cancer Control defines the key principles, attributes, methods, and tools needed to achieve the goal of implementing an effective national cancer control plan. This report describes the current structure of cancer control from a local to global scale, identifies necessary goals for the system, and formulates the path towards integrated disease control systems and a cancer-free future. This framework is a crucial step in establishing an effective, efficient, and accountable system for controlling cancer and other diseases.

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