Biographical Memoirs Volume 79 (2001) / Chapter Skim
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Julius H. Comroe, Jr.
Julius H. Comroe, Jr.
Pages 66-83
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From page 67... ...
KETY AND ROBERT E FORSTER r ULlUS COMROE WAS AN extraordinary teacher who began his meclical career as a surgeon, then became an accom~ [ishecl investigator en cl clicl important original research, but graclually clirectecl his consiclerable energies into teaching basic biomeclical research to graduate physicians en c!
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From page 68... ...
This was the end of his career in surgery, to the benefit of meclical science. In 1936 Julius Comroe marries!
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From page 69... ...
In 1927, before they reported chemosensitivity in the carotid bifurcation, Heymans en cl Heymans hacl also clescribec! a chemosensitive mechanism in the aortic arch region, but these results were challengecI, so the existence of aortic chemoreceptors was in dispute when Comroe started his investigations.
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From page 70... ...
. ~ 1 - _ _ tne explanation In Increased nerve traffic from contracting muscles and did find that stimulating peripheral muscle groups in man and anesthetized animals did increase ventilation, but not enough to account for the total increase seen in exercise (Comroe and Schmidt, ~ 943,2)
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From page 71... ...
His colleagues in pharmacology gave him a going-away party at which Comroe gave him a large wooden mallet with a tag saying "If all else fails, try this." The two men published many further papers together on clinically applied physiology and pharmacology, particularly related to anesthesiology, until Comroe left Philadelphia in 1957, but their joint productivity continued for the rest of their lives in spite of the 3,000 miles separating them. From 1944 to 1946 Comroe consulted for the Chemical Warfare Service, with a number of other distinguished pharmacologists and physiologists.
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From page 72... ...
Fahs Smith, partly in response to criticism in the FIexner report about graduate meclical education en cl with the hope of obtaining foundation support. Aciclitionally, two non-university-affiliated medical schools in Philadelphia had their builclings conclemnecl for urban reconstruction en cl were willing to turn their assets over to the University of Pennsylvania with the states!
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From page 73... ...
en c! continuous analysis of respiratory gases at the mouth, inclucling a nitrogen meter clevelopecl by John Lilly of the Johnson Founciation at Penn, a breath analysis mass spectrometer, the first practical one of its kincl (now in the DeWitt Stetten, fir., Museum of Meclical Research of the National Institutes of Health)
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From page 74... ...
from years in military service. This new course was structural around the major organ systems rather than around clepartmental clisciplines, with lectures en cl cliscussion proceeding logically through the basic sciences pertinent to each organ system: anatomy, histology, physiology, pharmacology, microbiology, and pathology, with frequent clinical correlations.
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From page 75... ...
He was invited to look at the chair in pharmacology at the Meclical School of the University of California in San Francisco. At that time the UCSF was a divided school with the clinical departments in San Francisco en cl the basic science departments in Berkeley across San Francisco Bay, where they hac!
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From page 76... ...
As Comroe himself pointed out (1983) , it took many individuals to procluce this change, en cl there were also propitious societal changes at the time, such as the burgeoning NIH support for research.
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From page 77... ...
the CVRI to help departments builcl strong research programs, providing space en cl funcis, but always insisting on the highest scientific stanciarcis. Not every department thanked!
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From page 78... ...
While on the National Heart Council, he realizecl how important it was to convince Congress and the public that supporting scientific study at the basic level was actually very practical. In 1971 his old friend Robert Dripps spent a sabhatical at the CVRT he and Tulius Comroe, using scientific en cl scholarly methods, began a monumental effort to investigate how many of the important new contributions of clinical medicine since the 1940s hacl clepenclecl on research that hacl been stimulatecl with the aim of contributing to meclical care en c!
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From page 79... ...
Julius Comroe publishecl nearly 200 scientific articles in his lifetime and wrote 4 books. He was asked to give many clistinguishecl namecl lectures, was electecl to the National Academy of Sciences, the American Academy of Arts en cl Sciences, and as a fellow of the Royal Academy of Physicians.
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From page 80... ...
In the 1960s Julius Comroe clevelopec! severe back pain that wouIcl not yielcl to conservative therapy en cl he wouIcl not consider surgery.
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From page 81... ...
Vascular relations of the aortic arch body in the dog.
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From page 82... ...
A comparison with a nitrogen washout method for measuring functional residual capacity in normal subjects.
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From page 83... ...
Sampson. Carotid sinus versus carotid body origin of nicotine and cyanide bradycardia in the dog.
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