The National Academies Press

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1. Introduction
Pages 12-16

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From page 12... ... This new paradigm of biomedical research has become possible in part through technological advances that allow for high-throughput data collection and analysis an approach referred to as "discovery science." Traditional biomedical research is conducted by small groups that test hypotheses and are interactive but not highly collaborative, whereas largescale biology often involves large, highly collaborative groups that deal with the high-throughput collection and analysis of large bodies of data. The two approaches can be synergistic in the long term when large-scale 12 Read the entire page →
From page 13... ... These characteristics may not mesh well with the traditional organization and operation of research institutions, especially with respect to funding mechanisms and peer review, ownership of intellectual property, scientific training, career advancement, and planning and management oversight within academic institutions. Many decisions must be made before a large-scale project is launched, such as where the funding will come from and how it will be made available to investigators; what projects and institutions will be funded; and how activities will be organized, managed, completed, and evaluated. Read the entire page →
From page 14... ... Because the concept of large-scale science is relatively new to the field of biomedical research, and there is increasing interest is using this research format to advance the study of cancer, the National Cancer Policy Board determined that it would be useful at this time to address some of the issues and questions outlined above. The purpose of the study documented in this report, then, was to: � Define the concept of large-scale biomedical science, with a particular focus on its application to cancer research. Read the entire page →
From page 15... ... Chapter 2 develops a working definition of "large-scale biomedical research" within the framework of this report. It also provides brief examples of the types of projects that may be amenable to the large-scale research approach, as well as a brief overview of the challenges and impediments involved in using this approach. Read the entire page →
From page 16... ... 16 LARGE-SCALE BIOMEDICAL SCIENCE Chapter 7 examines the role of intellectual property in biomedical research, with particular emphasis on the availability of large-scale data and research tools. Chapter 8 summarizes the key findings of the study and presents the committee's recommendations. Read the entire page →

From page 12...

... This new paradigm of biomedical research has become possible in part through technological advances that allow for high-throughput data collection and analysis an approach referred to as "discovery science." Traditional biomedical research is conducted by small groups that test hypotheses and are interactive but not highly collaborative, whereas largescale biology often involves large, highly collaborative groups that deal with the high-throughput collection and analysis of large bodies of data. The two approaches can be synergistic in the long term when large-scale 12

Read the entire page →

From page 13...

... These characteristics may not mesh well with the traditional organization and operation of research institutions, especially with respect to funding mechanisms and peer review, ownership of intellectual property, scientific training, career advancement, and planning and management oversight within academic institutions. Many decisions must be made before a large-scale project is launched, such as where the funding will come from and how it will be made available to investigators; what projects and institutions will be funded; and how activities will be organized, managed, completed, and evaluated.

Read the entire page →

From page 14...

... Because the concept of large-scale science is relatively new to the field of biomedical research, and there is increasing interest is using this research format to advance the study of cancer, the National Cancer Policy Board determined that it would be useful at this time to address some of the issues and questions outlined above. The purpose of the study documented in this report, then, was to: � Define the concept of large-scale biomedical science, with a particular focus on its application to cancer research.

Read the entire page →

From page 15...

... Chapter 2 develops a working definition of "large-scale biomedical research" within the framework of this report. It also provides brief examples of the types of projects that may be amenable to the large-scale research approach, as well as a brief overview of the challenges and impediments involved in using this approach.

Read the entire page →

From page 16...

... 16 LARGE-SCALE BIOMEDICAL SCIENCE Chapter 7 examines the role of intellectual property in biomedical research, with particular emphasis on the availability of large-scale data and research tools. Chapter 8 summarizes the key findings of the study and presents the committee's recommendations.

Read the entire page →

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1. Introduction Pages 12-16

1. Introduction
Pages 12-16