Designing Nanostructures at the Interface between Biomedical and Physical Systems Conference Focus Group Summaries (2005) / Chapter Skim
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Build a Glucose Sensor to Circulate (Implant) In Vivo in Humans and Regulate Insulin
Build a Glucose Sensor to Circulate (Implant) In Vivo in Humans and Regulate Insulin
Pages 45-52
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From page 45... ...
The development of reliable long-term functional implantable biosensors for continuous glucose monitoring has become of interest in the development of optimum treatment of diabetics. The Problem · Development of novel biocompatible implantable materials that can be processed using micro and nano processing techniques for fabricating glucose sensors · Development of novel micro and nano fabrication techniques to fabricate implantable devices as glucose sensors · Development of novel surface modification techniques for biomolecule immobilization to improve biocompatibility and functionality of implantable glucose sensors · Development of novel methods with high specificity and reliability for rapid and continuous detection of glucose level in vivo 45
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From page 46... ...
57: 81-84. FOCUS GROUP SUMMARY Summary written by: Jonathan Stroud, Graduate Student, Science Writing Program, University of Southern California Focus group members: · Ananth Annapragada, Associate Professor, Department of Bioinformatics, University of Texas Health Science Center at Houston · Andres Garcia, Associate Professor, Department of Mechanical Engineering, Georgia Institute of Technology · Eleni Kousvelari, Acting Director, Center for Biotechnology & Innovation, National Institute of Dental and Craniofacial Research · Greg Lanza, Assistant Professor of Medicine, Department of Medicine and Biomedical Engineering, Adjunct Assistant Professor of Biomedical Engineering, Washington University Medical Center · Peter Ma, Associate Professor, School of Dentistry, University of Michigan · G
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From page 47... ...
The Group 6 members first introduced themselves one by one, summarizing their diverse areas of expertise, which ranged from applied anthropology to tissue engineering. The members included Ananth Annapragada, an associate professor at the University of Texas Health Science Center at Houston; Andres Garcia, an associate professor at the Georgia Institute of Technology; Eleni Kousvelari, the acting director of the National Institute of Dental and Craniofacial Research; Greg Lanza, an assistant professor of medicine and adjunct assistant professor of biomedical engineering at Washington University Medical Center; Peter Ma, an associate professor at the University of
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From page 48... ...
"Diabetes is a complicated disease fundamentally associated with a lack of insulin, the hormone that helps regulate blood sugar," he said. "Diabetes mellitus has two distinct varieties: diabetes type I is an autoimmune disease found in younger patients, while diabetes type II occurs as a result of obesity and hypertension and normally develops in older patients," he said.
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From page 49... ...
The group then looked at an SMSI implantable sensor. The sensor, which is currently undergoing clinical trials, uses radio frequencies to broadcast glucose information to a receiver worn outside the body, has a 6 to 12 month shelf life, and is the size of a small, thin pill.
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From page 50... ...
Roessner suggested a tiny implantable sensor capable of transmitting reliable glucose data to receptors outside the body, not unlike the SMSI glucose sensor, only smaller, more reliable, and with a longer device lifetime. Kousvelari proposed an intra-dental implant residing in a false tooth, an idea Stone seconded and expanded on.
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From page 51... ...
"The interchange and exchange that went on was superb." Group members said that, while they did not believe the group developed any novel ideas, they thought the interdisciplinary nature of the discussion was enriching and significant. "We spent a lot of time debating the social and ethical implications of this technology," Annapragada said.
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