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Pages 280-285

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From page 280...
... TABLE 1 Dietary Reference Intakes for Thiamin by Life Stage Group DRI values (mg/day) EARa RDAb AIc ULd males females males females Life stage group 0 through 6 mo 0.2 7 through 12 mo 0.3 1 through 3 y 0.4 0.4 0.5 0.5 4 through 8 y 0.5 0.5 0.6 0.6 9 through 13 y 0.7 0.7 0.9 0.9 14 through 18 y 1.0 0.9 1.2 1.0 19 through 30 y 1.0 0.9 1.2 1.1 31 through 50 y 1.0 0.9 1.2 1.1 51 through 70 y 1.0 0.9 1.2 1.1 > 70 y 1.0 0.9 1.2 1.1 Pregnancy £ 18 y 1.2 1.4 19 through 50 y 1.2 1.4 Lactation £ 18 y 1.2 1.4 19 through 50 y 1.2 1.4 a EAR = Estimated Average Requirement.
From page 281...
... PART III: THIAMIN 281 THIAMIN T hiamin, also known as vitamin B1 and aneurin, functions as a coenzyme in the metabolism of carbohydrates and branched-chain amino acids. Only a small percentage of a high dose of thiamin is absorbed, and elevated serum values result in active urinary excretion of the vitamin.
From page 282...
... DRIs: THE ESSENTIAL GUIDE TO NUTRIENT REQUIREMENTS 282 DETERMINING DRIS Determining Requirements The adult requirements for thiamin are based on metabolic studies in which urinary thiamin was measured during depletion–repletion, along with the mea surement of erythrocyte transketolase activity. Special Considerations Individuals with increased needs: People who may have increased needs for thiamin include those being treated with hemodialysis or peritoneal dialysis, individuals with malabsorption syndrome, and women who are carrying more than one fetus or breastfeeding more than one infant.
From page 283...
... PART III: THIAMIN 283 thiamin could not be determined. Although no adverse effects have been associated with excess intake of thiamin from food or supplements, this does not mean that there is no potential for adverse effects resulting from high intakes.
From page 284...
... DRIs: THE ESSENTIAL GUIDE TO NUTRIENT REQUIREMENTS 284 • Mental changes such as apathy, decreased short-term memory, confu sion, and irritability • Muscle weakness • Cardiovascular effects such as enlarged heart In developing nations, thiamin deficiency often manifests as beriberi. In "wet beriberi," edema occurs.
From page 285...
... PART III: THIAMIN 285 KEY POINTS FOR THIAMIN Thiamin (also known as vitamin B1 and aneurin) functions as a 3 coenzyme in the metabolism of carbohydrates and branched chain amino acids.

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