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Pages 350-355

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From page 350...
... TABLE 1 Dietary Reference Intakes for Manganese by Life Stage Group DRI values (mg/day) AIa ULb males females Life stage group NDc 0 through 6 mo 0.003 0.003 7 through 12 mo 0.6 0.6 ND 1 through 3 y 1.2 1.2 2 4 through 8 y 1.5 1.5 3 9 through 13 y 1.9 1.6 6 14 through 18 y 2.2 1.6 9 19 through 30 y 2.3 1.8 11 31 through 50 y 2.3 1.8 11 51 through 70 y 2.3 1.8 11 > 70 y 2.3 1.8 11 Pregnancy £ 18 y 2.0 9 19 through 50 y 2.0 11 Lactation £ 18 y 2.6 9 19 through 50 y 2.6 11 a AI = Adequate Intake.
From page 351...
... PART III: MANGANESE 351 MANGANESE M anganese is involved in the formation of bone and in specific reac tions related to amino acid, cholesterol, and carbohydrate metabo lism. Manganese metalloenzymes include arginase, glutamine synthetase, phosphoenolpyruvate decarboxylase, and manganese superoxide dismutase.
From page 352...
... DRIs: THE ESSENTIAL GUIDE TO NUTRIENT REQUIREMENTS 352 trahepatic tissues by transferrin and possibly a2-macroglobulin and albumin. Excretion primarily occurs in the feces.
From page 353...
... PART III: MANGANESE 353 Based on the Total Diet Study, the highest dietary manganese intake at the 95th percentile was 6.3 mg/day, which was the level consumed by men aged 31 to 50 years. Data from the Third National Health and Nutrition Examination Survey (NHANES III, 1988–1994)
From page 354...
... DRIs: THE ESSENTIAL GUIDE TO NUTRIENT REQUIREMENTS 354 TABLE 2 Potential Interactions with Other Dietary Substances Substance Potential Interaction Notes SUBSTANCES THAT AFFECT MANGANESE Calcium Calcium may reduce In one study, adding calcium to human milk reduced manganese absorption. the absorption of manganese from 4.9 percent to 3.0 percent.
From page 355...
... PART III: MANGANESE 355 KEY POINTS FOR MANGANESE Manganese is an essential nutrient involved in the formation of 3 bone and in specific reactions related to amino acid, cholesterol, and carbohydrate metabolism. Since data were insufficient to set an EAR and thus calculate 3 an RDA for manganese, an AI was instead developed.

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