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Exploring the Role of Antiviral Drugs in the Eradication of Polio Workshop Report (2006) / Chapter Skim
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5 Implementation and Recommendations
Pages 47-50

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From page 47...
... Second, the risk of accidental or intentional release of poliovirus cannot be entirely eliminated and the consequences of such a release will grow more and more serious after routine immunization ceases. Therefore, the committee concludes that if current plans to cease OPV administration go forward, it is important to begin development of at least one, but preferably two, polio antiviral drugs as a supplement to the tools currently available for the control of poliomyelitis outbreaks.
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From page 48...
... The development of one or more polio antiviral drugs should be included as a goal of the global polio eradication effort. Under the assumption that administration of OPV will eventually be halted, the availability of an effective polio antiviral will be extremely useful for outbreak control in the context of declining levels of population immunity.
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From page 49...
... Improved understanding of the sites of replication and the develop ment of appropriate animal models of infection, pathogenesis and shedding will make the development of a polio antiviral much more likely to succeed.
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Key Terms

  • polio antiviral
  • polio eradication
  • public health


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