Funding Biomedical Research Programs Contributions of the Markey Trust (2006) / Chapter Skim
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Appendix A Overview and Description Lucille P. Markey Charitable Trust Research Program Grants Awards
Appendix A Overview and Description Lucille P. Markey Charitable Trust Research Program Grants Awards
Pages 53-74
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Research focused on understanding the control of transcription at the molecular level and the behavior of the receptor at the whole-animal level. Most funding was utilized for equipment and supplies to support pilot projects and to explore new areas of research (includes $1,155,000 in supplemental funding awarded in 1988 and $300,000 awarded in 1991)
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. The grant supported expansion of the Developmental Biology Center by attracting new faculty, upgrading instrumentation, and creating an intramural research funding program.
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Markey funds were supplemented by those from NSF and NIH. In addition to major equipment purchases and lab support, funding was used for faculty support, recruiting, visits, seminar speakers, and support personnel.
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The research investigated the essential link between structural biology and biochemistry and determined the organization of the macromolecular assemblies that constitute living structures. The grant provided faculty support, graduate student stipends, and major equipment purchases.
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The grant supported 10 research projects for individual faculty ranging from molecular biology of receptor signal transduction to behavioral genetics to regulation of nicotinic acetylcholine receptor expression and six core projects. The goal was to determine the manner in which proteins are inserted into membranes and the environ 2 Includes supplemental funds of $500,000 made in recognition of outstanding progress by Markey-supported investigators made in FY 1997.
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. The grant supported the study of somatic cell genetics and recombinant DNA and molecular understanding of human diseases and studies on mutagenesis, with emphasis on the mechanisms by which cyclic AMP (adenosine monophosphate)
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In addition to salaries, the grant funded major equipment purchases and renovations. Jeremy Berg was the PI.
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Funds covered partial support for 10 new junior faculty, supplies for these faculty, major equipment purchases, and support for postdocs and technicians. Research focused on molecular genetics, cell and developmental biology, immunology, and chemical carcinogenesis and molecular pharmacology.
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Markey funds supported programs that focused on interdisciplinary investigation of the molecular basis of cell proliferation, and the control of cell division by the Departments of Biochemistry, Biophysics and Genetics, Microbiology and Immunology, Pharmacology and Medicine. Funding supported renovation of a core facility, salary and start-up costs for new faculty, and graduate and postdoctoral training.
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Funding provided sal 1Includes supplemental funds of $500,000 made in recognition of outstanding progress by Markey-supported investigators addressing important problems in biomedical sciences awarded in FY 1996.
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The center's mission was to determine the fundamental processes by which brain molecules and cells develop in newborns to facilitate perception, movement, learning, and memory. The award provided salary and start-up costs for new faculty, salary support for lab technicians and stipends for graduate students and postdoctoral fellows, and equipment purchases.
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Research focused on the study of molecules responsible for cell-cell communication via chemical and electrical synapses, cell motility and cell division, regulation of the cell cycle, and transport from nucleus to cytoplasm. The award provided faculty salary, start-up support for new faculty, stipends for postdoctoral fellows and graduate students, and support for the purchase of major equipment.
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A major function of the center was to encourage and support interaction among structural biologists, molecular geneticists, and biochemists and to promote understanding of how the structure of RNA influences its biological properties. Funding was used primarily for major equipment purchases, faculty start-up costs, and postdoctoral fellow stipends.
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Funding provided salary and start-up costs for faculty, stipends for graduate students and postdoctoral fellows, and equipment purchases. Kurt Isselbacher was the PI.
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In addition, the grant established two core laboratories to support these programs -- one for molecular instrumentation and a core animal facility. Funds were used for faculty salary and start-up costs, construction, major equipment purchases, and support of the core laboratories.
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. The grant supported an interdisciplinary program to study the molecular and cell biology of disease.
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Research focused on investigation of the path from drug susceptibility behavior to the chromosomal location of a single "drug abuse gene" and to the electrophysiological and behavioral effects of mutating those genes in intact mice. Markey funds supported pilot projects and core facilities including: gene map
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Funding provided faculty salaries, graduate student stipends, and equipment purchases. Gary Goldstein and John Laterra were the PIs.
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The research focused on brain plasticity and specifically on the study of mechanisms for modulating neuropsychaiatric disorders. Markey funds were used to provide stipends for postdoctoral fellows and for initial support for young investigators.
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The goal of the grant was to identify the unique molecular mechanisms by which the eye creates and sustains a local microenvironment that suppresses immunologic inflammation, and explains the phenomena of immune privilege. Funds provided salary support for a primary investigator, technicians, and the purchase of major equipment.
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real-time neural network simulations. Funds supported major equipment purchases for the Center and start-up costs for new faculty.
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Funds provided faculty salary and start-up costs. Kenneth Foon was the PI.
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