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Appendix B Site Visit Reports Lucille P. Markey Charitable Trust Large Research Program Grant Awards
Pages 75-86

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From page 75...
... Boyer and the Howard Hughes Medical Institute had funded the Boyer Center building. The $12.1 million Markey funds were originally planned for developing the Program in Molecular Oncology, a part of the Boyer Center in July 1990.
From page 76...
... Tian Xu came to the Boyer Center from the University of California, Berkley, as a postdoctoral fellow in 1993. Although he was offered an HHMI fellowship at that time, the Boyer Center provided larger lab space and more equipment than most junior faculty received.
From page 77...
... While the dollars were used well to catalyze an individual scientist's career development, it appears that they were not used to develop a coherent program of molecular oncology. Conclusions Other than support for a few young scientists, three of whom remain at Yale, the site visit team could find no evidence of a lasting legacy of Markey funds at the Boyer Center.
From page 78...
... 4. The Program in Molecular Oncology was able to build bridges to the clinical departments, but was unable to build similar bridges to the basic science departments.
From page 79...
... In 1987, UCSF applied to the Markey Charitable Trust for funds to form a unified program of research and graduate teaching that would unify biomedical research on the UCSF campus. The purpose was to foster and exploit unity and collaboration among the research faculty and
From page 80...
... During the period of Markey support between 1988 and 1995, PIBS assumed the responsibility for graduate education previously divided among the basic science departments and created a collaboration with basic science and clinical departments for recruiting to UCSF outstanding young scientists. Using Markey support, PIBS collaborated with clinical and basic science departments in 21 successful recruitments, who have established creative research programs of international note.
From page 81...
... All programs that are members of PIBS have agreed to a common governance including common and rigorous standards for participation by the faculty membership, periodic review of the faculty in each program, shared scrutiny of applicants for open positions, and common standards for graduate admissions and teaching. PIBS sponsors an annual retreat for each of its graduate programs, an orientation day for new students, a weekly faculty-student journal club, an annual course in the Practice of Science, and other activities.
From page 82...
... THE WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH MASSACHUSETTS INSTITUTE OF TECHNOLOGY PROGRAM IN BIOMEDICAL SCIENCES MARCH 2001 The site visit team had an informal dinner meeting with Gerald Fink, Director, Whitehead Institute; John Pratt, Associate Director, Whitehead Institute; and Eve Nichols, Director of Institutional Advancement. Whitehead representatives described the Whitehead Institute and Markey's role in developing the careers of young faculty and promising scientists.
From page 83...
... For the Whitehead faculty and Whitehead Fellows, seed money from the Markey Trust led the development of sophisticated research programs, which were subsequently supported by the NIH and other traditional funding sources. In addition to advancing the careers of exceptional young scientists, the Markey Trust award had an important impact on the evolution of the Whitehead Institute as a whole.
From page 84...
... He has also created microelectromechanical devices to track biomolecular interactions and enhance the identification of human disease genes. Terry Orr-Weaver was appointed as an assistant professor in 1987.
From page 85...
... Visit to Genome Lab The site visit team had the opportunity to visit Eric Lander's genome laboratory, which is one of the national labs for the Human Genome Project. Over the last few years Dr.
From page 86...
... was used to fund new and promising researchers. These scientists were either undergoing a change in career directions or a change in research interest and probably would not have received adequate funding to make these changes without the Markey award.


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