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Appendix H Open Meeting Agenda
Pages 110-114

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From page 110...
... Appendix H Open Meeting Agenda COMMITTEE ON DOD'S MALARIA VACCINE RESEARCH- A PROGRAM REVIEW January 23­25, 2006 Courtyard by Marriott 8506 Fenton St. Silver Spring, MD 20910 Tel 301-589-4899 Meeting Room AGENDA Meeting Objectives · Obtain perspectives from DoD on the malaria threat to the force · Review DoD's P
From page 111...
... APPENDIX H 111 Monday, January 23, 2006 Closed Session 8:00 Bias and Conflict Discussion Susanne Stoiber Executive Director, Institute of Medicine Open Session 9:00 MIDRP Welcome COL David Vaughn, MC Director, Military Infectious Disease Research Program Fort Detrick, Maryland 9:15 Chairman's Remarks and Introductions 9:30 MIDRP and Malaria Program Overview and Review of Committee Charge COL David Vaughn 10:30 Break 11:00 Overview Malaria Vaccine Development Dr. Filip Dubovsky Scientific Director, Malaria Vaccine Initiative 12:00 Lunch 1:00­5:15 Program Review -- Protein-based vaccine strategy 1:00 Objectives and Strategy COL Gray Heppner 1:30 Progress towards an RTS,S-Based Vaccine by Year 2010: New Adjuvants, Antigens, and Vectors · Status of RTS,S/AS02A COL Gray Heppner · Adjuvant AS01B: RTS,S/AS02A vs.
From page 112...
... 112 APPENDIX H 2:50 Break 3:00 Clinical Trials of an RTS,S-Based Vaccine COL Gray Heppner 3:30 Future Vaccines · Antigen Discovery COL Chris Ockenhouse · Vivax COL Chris Ockenhouse · Attenuated Knock-out COL Gray Heppner 4:00 Building the RTS,S-Based Vaccine · One Allele or Two? COL Chris Ockenhouse · The role of molecular analyses · Making Development Earlier COL Chris Ockenhouse · The potential microarrays · Assays of Immune Response Dr.
From page 113...
... APPENDIX H 113 Tuesday, January 24, 2006 Open Session 8:00­12:30 Program Review -- DNA-based vaccine strategy 8:00 Objective, Background & Rationale CAPT Tom Richie 8:30 Program History CAPT Tom Richie 8:50 Functional Elements & Activities · Overview CAPT Tom Richie · Discovery Research Dr. Denise Doolan · Target Antigens · Immune Mechanism 9:50 Break (30 minutes)
From page 114...
... 114 APPENDIX H Wednesday, January 25, 2006 Closed Executive Session* 8:00­12:00 Structured discussion of the DoD malaria vaccine research program · Clarify gaps or missing information · Finish discussions regarding key program questions · Develop initial findings and recommendations · Establish second meeting date to review report draft.

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