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8 Naval Health Research Center San Diego Avian and Pandemic Influenza Activities
Pages 167-182

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From page 167...
... . NHRC was instrumental in demonstrating increased adenoviral morbidity among basic trainees after loss of vaccine in the late 1990s, and it remains involved in the restoration of the adenovirus vaccine program by supporting current clinical trials at basic training centers (NHRC, 2006b)
From page 168...
... Committee for the Assessment of DoD-GEIS Influenza Surveillance and Response Programs visited NHRC on March 26-27, 2007. A list of the people met and interviewed and the itinerary followed can be found at the end of this chapter. MANAGEMENT AND PLANNING Administrative support for NRDL is provided by the DoD Center for Deployment Health Research at the time of the IOM review.
From page 169...
... The stated objectives of NRDL are to help enhance febrile respiratory and influenza surveillance, advance influenza diagnostics, and improve influenza field diagnostics as well as to assist with the coordination of overseas response capabilities, with the early detection of and response to respiratory disease, with enhanced communication within DoD, and with maintaining the health of U.S. military forces worldwide (NHRC, 2006a)
From page 170...
... Historically, military training centers have been associated with seasonal respiratory outbreaks during the first few weeks of training and have been ideal populations for FRI and influenza surveillance (Faix, 2006)
From page 171...
... RECOMMENDATION 8-1. NRDL should investigate factors con tributing to the ability or inability of the eight military training sites to meet maximum FRI surveillance targets as well as continue to explore methods to validate the reliability of vaccine-effectiveness data, which are available from no other populations on a consistent basis.
From page 172...
... If more rapid testing is warranted, arrangements are made to transport samples to NRDL as soon as possible. In addition to influenza surveillance, the findings would help define the relative importance of pathogens responsible for FRI, describe shipboard transmission, lead to appropriate preventive measures, and help maintain ship readiness.
From page 173...
... California-Mexico Border FRI Surveillance Surveillance among the cross-border civilian population began in 2004 as a collaborative effort with the CDC, the San Ysidro Health Center (San Diego Co.) , and Clinicas de Salud del Pueblo, Calexico (Imperial Co.)
From page 174...
... in increasing sample collection and processing at its five base sentinel sites in Japan and is interfacing with Seventh Fleet preventive medicine personnel to provide FRI surveillance for upcoming deployment and exercises. Conclusions Establishment of the Pacific Rim surveillance hub is a logical extension of current NRDL surveillance activities.
From page 175...
... Supplemental 2006 funding greatly enhanced capacity for influenza surveillance and detection. Laboratory surge capacity has been increased,
From page 176...
... • NHRC provided weekly updates that included influenza and FRI rate data to surveillance partners throughout the year. • NHRC provided rapid laboratory confirmation of adenoviral etiology during FRI rate spikes that were identified by the FRI surveillance
From page 177...
... Although the advanced diagnostic equipment may not be able to test all TABLE 8-1  Summary of Surge Capability at the NRDL, NHRC Condition PCR T-5000 Total Routine operation 168/week 168/week 336/week Altered algorithm -- 672/week 440/week 1,112/week influenza A and H5 first Target only specific gene 1,548/week 440/week 1,988/week 24-hour operations 3,528/week 1,232/week 4,760/week SOURCE: NHRC, 2007.
From page 178...
... Ties are close with training sites, fleet commands, and each of the overseas laboratories. By design there are no direct collaborations with foreign governments or international organizations; NHRC relies instead on the naval medical research units and fleet bases to provide those channels.
From page 179...
... 2006. Febrile respiratory illness surveillance and research at Naval Health Research Center: Evaluating unique populations.
From page 180...
... Kevin Russell 0900-0940 Discussion about febrile respiratory illness surveillance in U.S. military basic training centers Tony Hawksworth 0940-1010 Discussion about global naval shipboard surveillance Cmdr.
From page 181...
... Navy ship 1500-1600 Tour of branch medical clinic at Marine Corps Recruit Depot Tuesday, March 27, 2007 0800-0830 Breakfast 0830-0850 Welcome remarks and introduction to MRDL research projects Cmdr. Kevin Russell 0850-0920 Discussion about laboratory testing Miguel Angel Osuna 0920-1000 Discussion about the sequencing of 100 percent of influenza isolates Dr.


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