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4 Armed Forces Research Institute of Medical Sciences Thailand Avian and Pandemic Influenza Activities
Pages 81-96

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From page 81...
... Army under the overall command of a Royal Thai Army officer of flag rank. Historically, AFRIMS has been closely linked with a Royal Thai Army laboratory and also collaborates with various other national institutions, including the Thai Ministry of Health (Department of Medical Sciences, National Institute of Health, Department of Communicable Disease Control, and the Office of the Permanent Secretary and its Field Epidemiology Training Program)
From page 82...
... Collaborating Center for Diagnostic Reference, Training, and Investigation of Emerging Infectious Diseases. The projects undertaken by AFRIMS using the fiscal year 2006 AI/PI supplemental funding included increasing the laboratory infrastructure and capabilities of AFRIMS laboratories in Bangkok, Thailand, as well as performing regional influenza surveillance, particularly for highly pathogenic avian influenza (see Figure 4-1)
From page 83...
... . In addition to Thailand, eight countries in South and Southeast Asia have reported highly pathogenic avian influenza among poultry: Bangladesh, Cambodia, India, Indonesia, Laos, Malaysia, Myanmar, and Vietnam.
From page 84...
... Conclusions While AFRIMS made appropriate use of the supplemental funding, the site visit team concluded that a minimum of two years of funding for supplemental influenza surveillance is desirable, and a five-year funding package would be ideal. Ideally, a novel, modest, and stable funding stream would be created to allow for proper planning and program implementation as well as for surge capacity in the face of an unexpected outbreak situation.
From page 85...
... Within Thailand, AFRIMS is expanding influenza surveillance programs through its relationship with the Royal Thai Army (AFRIMS, 2007a)
From page 86...
... Conclusions The Committee concluded that AFRIMS's influenza surveillance protocol activities and initiatives expanded with supplemental funding represented a significant contribution to the influenza surveillance network in the region. In addition, the committee concluded that AFRIMS would greatly extend its contribution to knowledge of the H5N1 influenza virus with additional protocols focused on seasonal influenza and novel findings.
From page 87...
... RESPONSE CAPACITY Under routine conditions, the AFRIMS respiratory laboratory is capable of performing molecular screening of 200 samples per week. Additionally, the field sites at the Kwai River Christian Hospital and in Kangphaeng Phet are each capable of screening an additional 100 samples per week, bringing the total capacity to 400 samples per week (AFRIMS, 2007b)
From page 88...
... Conclusions AFRIMS has developed a plan and a chain of command to convert expendable research and other laboratory activities to support enhanced surveillance should human-to-human transmission by a novel avian influenza
From page 89...
... The cost of this biosafety capacity is approximately $2 million, all of which comes from the supplemental funding. The respiratory laboratory in Bangkok will have the capability for molecular diagnosis as well as subtyping strains to distinguish significant variants among the seasonal influenza isolates and to recognize strains that may emerge as candidate pandemic strains.
From page 90...
... Conclusions The IOM site visit team feels it a wise decision for AFRIMS to expand its diagnostic capabilities as this will allow it to culture H5N1 and other highly pathogenic strains of avian influenza virus as well as strains that may evolve or be recognized in the future. In conjunction with the expansion of the laboratory capabilities, AFRIMS will need to increase the number of trained personnel.
From page 91...
... During the IOM team's meeting with the International Emerging Infections Program (IEIP) , it was explained that two of the program's planned influenza studies intend to include a collaboration with AFRIMS.
From page 92...
... . AFRIMS (Armed Forces Research Institute of Medical Sciences)
From page 93...
... Peruski, International Emerging Infections Program, Centers for Disease Control and Prevention/Thailand Ministry of Public Health, Nonthaburi, Thailand Wiwan Sanasuttipun, International Emerging Infections Program, Centers for Disease Control and Prevention/Thailand Ministry of Public Health, Nonthaburi, Thailand Somsak Thamthitiwat, International Emerging Infections Program, Centers for Disease Control and Prevention/Thailand Ministry of Public Health, Nonthaburi, Thailand Malinee Chittaganpitch, National Institutes of Health, Bangkok, Thailand Rungrueng Kitphati, National Institutes of Health, Bangkok, Thailand Krongraew Supawat, National Institutes of Health, Bangkok, Thailand
From page 94...
... Adinkani, Institute of Medicine, Kathmandu, Nepal Manas Kumar Banerjee, Epidemiology and Disease Control Division of Department of Health Services, Kathmandu, Nepal Sarala Malla, Ministry of Health and Population, Department of Health Services, National Public Health Laboratory, Kathmandu, Nepal Jeetendra Man Shrestha, Epidemiology and Disease Control Division of Department of Health Services, Kathmandu, Nepal Sailesh B Pradhan, Kathmandu Medical College Teaching Hospital, Kathmandu, Nepal Manohar Prasad Gupta, Tribhuvan University Teaching Hospital, Kathmandu, Nepal Yagya Laxmi Shakya, Tribhuvan University Teaching Hospital, Kathmandu, Nepal Prativa Pandey, CIWEC Clinical Travel Medicine Center, Kathmandu, Nepal Margarita Ronderos, World Health Organization Country Office for Nepal, Kathmandu, Nepal Kan Tun, World Health Organization Country Office for Nepal, Kathmandu, Nepal Prakash Ghimire, Programme for Immunization of Preventable Diseases, World Health Organization, Kathmandu, Nepal
From page 95...
... Sweeney 0930-1030 Overview of GEIS program 1030-1045 Break 1045-1130 Briefing on BSL-3 1130-1215 Lunch 1215-1330 Tour of AFRIMS main building 1330-1345 Return to Vet Med 1345-1445 Overview of Department of Immunology and Medicine avian influenza program 1445-1545 Overview of RTA influenza surveillance Enterics department 1545-1615 Briefing on Department of Veterinary Medicine 1615-1700 Tour of Vet Med and BSL-3 suite construction site 1700-1730 Return to hotel Tuesday, March 13, 2007 0800-1000 Briefing on Department of Virology 1000-1015 Break 1015-1145 Meeting with USAID personnel and state department science and tech officer 1145-1230 Lunch 1230-1315 Travel to Ministry of Public Health (MoPH) 1315-1445 Meeting with IEIP staff and MoPH representatives 1445-1500 Break 1500-1645 Continued discussions with MoPH representatives 1645-1745 Return to hotel
From page 96...
... Manas Kumar Banerjee, Director of EDCD  Jeetendra Man Shrestha, avian influenza coordinator Dr. of EDCD  Margarita Ronderos, WHO medical officer and UN Dr.


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