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Biographical Memoirs Volume 59 (1990) / Chapter Skim
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Solomon A. Berson
Pages 54-71

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From page 55...
... His father, a Russian emigre who studied chemical engineering at Columbia University, went into business and became a reasonably prosperous fur dyer and the owner of his own company. He was a competent mathematician, enjoyed chess, and played duplicate bridge sufficiently well to become a life master.
From page 56...
... and a fellowship to teach anatomy at the NYU Dental School, where his brother, Manny, was a student. He was finally admitted to New York University Medical School in 1941 and, a member of Alpha Omega Alpha honorary medical fraternity, received his M.D.
From page 57...
... in the circulation and the kinetic processes governing its synthesis and degradation. Shortly thereafter the two researchers used insulin labeled with radioactive iodine to test the hypothesis that cliabetes of the maturity-onset type was clue to an excessively rapid degradation of normally-secretec!
From page 58...
... A series of standard reactions containing labeled ligand and progressively increasing amounts of unlabeled ligand is prepared simultaneously exactly as above. With increasing amounts of unlabeled ligand, progressively increasing amounts of labelled ligand will be displaced from the antibody.
From page 59...
... Most scientists at that time believed that insulin did not produce antibodies, though Berson and Yalow, building on the work of others, had demonstrated that animal insulins used for the treatment of diabetes ctid, in fact, produce antibodies in man. (In guinea pigs they had observed specific, high-affinity antibodies to animal insulins that reacted well with human insulin.)
From page 60...
... Dr. Berson received numerous awards for this work, including the ~ 97 ~ Gairciner Award, the ~ 97 ~ Dickson Prize, the 1965 Banting Memorial Lecture and Banting Medal of the American Diabetes Association, the 1960 William S
From page 61...
... Berson continued his research at the Radioisotope Service until his death, but in 1968 accepted the professorship and chairmanship of the Department of Medicine, at the Mount Sinai School of Medicine of the City University of New York. In this position, he influenced many medical students and house staff.
From page 62...
... 62 BIOGRAPHICAL MEMOIRS thoughtfully reviewing articles. He was a member of many boards and advisory councils, several with the National Institutes of Health.
From page 63...
... The use of K42 or p32 labeled erythrocytes and IT tagged human serum albumin in simultaneous blood volume determinations.
From page 64...
... Quantitative aspects of iodine metabolism. The exchangeable organic iodine pool, and the rates of thyroidal secretion, peripheral degradation and fecal excretion of endogenously synthesized organically bound iodine.
From page 65...
... Plasma insulin concentrations in nondiabetic and early diabetic subjects. Diabetes, 9:254-60.
From page 66...
... Immunochemical distinction between insulins with identical amino acid sequences from different mammalian species (pork and sperm whale insulins)
From page 67...
... Reaction of fish insulins with human insulin antiserums: Potential value in the treatment of insulin resistance.
From page 68...
... Separation of antibodybound and unbound peptide hormones labeled with iodine131 by talcum powder and precipitated silica. Nature,212:35557.
From page 69...
... Size and charge distinctions between endogenous human plasma gastrin in peripheral blood and heptadecapeptide gastrins. Gastroenterology, 58:609-15.
From page 70...
... Plasma gastrin and gastric acid responses to sham feeding and feeding in dogs. Gastroenterology, 63:51-59.


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