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MANAGEMENT PROCEDURES
Pages 22-37

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From page 22...
... Personnel working in quarantine areas should be required to wear protective garments, including cap, mask, gloves, and protective footwear, as directed, and to observe all other prescribed safety precautions. All handling equipment, such as nets, transfer boxes, and gloves, should not be removed from the quarantine area, and should be sanitized daily.
From page 23...
... They are intended to provide the animals with the care and comfort they cannot provide for themselves in a laboratory environment. Environmental Control VENTILATION Ventilation should be considered in relation to the density of the animal population, the species of animals housed, and the nature of the laboratory activity.
From page 24...
... Feeding Food should be available daily unless otherwise indicated for health or scientific reasons. It should be palatable and of sufficient quantity and nutritive value to meet the normal daily requirements (Nutrient Requirements of Laboratory Animals, NAS-NRC Pub.
From page 25...
... Information on rearing chimpanzees can be obtained from the Delta Regional Primate Research Center, Covington, Louisiana 70433; the 6571st Aeromedical Research Laboratory, Holloman Air Force Base, New Mexico 88330; and the Yerkes Regional Primate Research Center, Emory University, Atlanta, Georgia 30322. Infant Care The mother of a newborn primate usually eats the placenta and membranes and in the process cuts the cord and cleans the infant.
From page 26...
... A weight loss of 10 percent usually occurs during the first 36 hours after birth. Normal, healthy infants usually regain their birth weight by 5 days of age.
From page 27...
... Tap water should be used as the diluent. Bottles containing newly prepared formula should be sterilized.
From page 28...
... By day 4 the formula should be fed full strength to Old World monkeys; the 1:1 ratio should be continued for baboons until weaning. Between the second and the fifth day, a strong, vigorous infant can be started on a self-feeding, ad libitum feeding schedule.
From page 29...
... commercial human-milk-substitute baby formula. These are referred to under "First Stage" and "Second Stage." Experienced laboratories have successfully reared Old World monkey infants on a formula in which the standard concentration of 20 calories per fluid ounce was followed.
From page 30...
... When they are about 6 months old, they may be placed entirely on an adult feeding schedule. Basically, weaning consists in decreasing the milk intake and increasing the intake of solid food, such as commercial monkey diet and fruit, and maintaining adequate daily caloric intake while the change is in progress.
From page 31...
... 200 \so too \7S 235 295 355 4I5 CONCEPTIONAL AGE (DAYS) 475 FIGURE 8 Caloric intake of infant rhesus macaque monkeys (Macaca mulatta)
From page 32...
... The effect of the parasite on the health of the animal is considered to be of minor significance unless the respiratory system is heavily involved. Enteric Diseases Enteritis is probably the most common of the diseases affecting laboratory primates.
From page 33...
... PERSONNEL MANAGEMENT The reliability of biomedical data obtained from laboratory primates depends largely upon sound preventive medicine practices, rigid environmental control, and the services of highly motivated and properly trained animal technicians. References and source materials for technician training are available from the Institute of Laboratory Animal Resources, National Research Council, 2101 Constitution Avenue, Washington, D.C.
From page 34...
... Employees should have physical examinations annually and chest x-rays and tuberculin tests semiannually. An immunization program should be maintained for all employees.
From page 35...
... Maximum food consumption is stimulated when moderate portions of of fresh food are offered at regular intervals during the day. Tupaia infants have been successfully hand-reared from birth on the following formula: 2/3 pint whole cow's milk, 1/3 pint evaporated milk, 1/2 raw egg yolk, and 1 teaspoon corn syrup.
From page 36...
... Baboons Commercial rations adequately fortified with minerals and vitamins are usually suitable for routine colony maintenance. A formula with the following analysis has been found satisfactory: carbohydrate, 46.70 percent; fat, 9.35 percent; protein, 20.85 percent; CA/P, 1 to 1.2; calories per 100 g, 354.
From page 37...
... Tattoos, neck chains, or collars may be used for this purpose. Records on experimental animals are essential to good animal care.


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