Indoor Allergens Assessing and Controlling Adverse Health Effects (1993) / Chapter Skim
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Glossary
Glossary
Pages 284-292
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From page 284... ...
A chemical or biological substance (e.g., pollen, animal dander, or house dust mite proteins) that causes an allergic reaction, characterized by hypersensitivity.
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Atopy. The state of having one or more of a defined group of diseasesallergic rhinoconjunctivitis, allergic asthma, and atopic dermatitis-that are caused by a genetic propensity to produce IgE antibodies to environmental allergens encountered through inhalation, ingestion, and, possibly, skin contact.
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Dermatophagoides pteronyssinus. A common cosmopolitan sarcoptiform mite commonly found in house dust accumulations and thought to be a contributory cause of atopic house dust asthma.
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A substance released by basophils in mast cells during allergic reactions. The pharmacologic effects of histamine include dilating blood vessels and stimulating gastric secretion.
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To deliberately introduce an antigenic substance (vaccination or active immunization) or antibodies (passive immunization)
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Connective tissue cells commonly found adjacent to blood vessels and in the lymphatic system, skin, lung, and other tissues. Mast cells are approximately 20 ,u in diameter and have cytoplasm filled by numerous (30-100)
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Such antibodies have the same combining site, the same light chain, and the same immunoglobulin class, subclass, and allotype, and their production in tissue culture by the hybridoma technique has enormously expanded the availability of highly characterized and specific antibodies of far-reaching practical and experimental importance. Monoclonal antibodies are occasionally found in human disease, as in cold hemolytic antibody disease, or after immunization of experimental animals, as with bacterial polysaccharides, but most antibody formation in viva is highly polyclonal.
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Obtaining food by absorbing dissolved organic material. Sensitization.
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Flare (1) The red outermost zone of the "triple response" (Sir Thomas Lewis)
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