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Non-Invasive Neuromodulation of the Central Nervous System Opportunities and Challenges: Workshop Summary (2015) / Chapter Skim
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5 Using Non-Invasive Neuromodulation for Diagnosis and Research
Pages 41-44

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From page 41...
... (Chen) • These techniques may also be useful to assess disease progression, predict response to therapy, presurgically map eloquent areas of the brain that should be protected during surgery, and employ as a re search tool to better understand the neurobiologic processes underly ing normal and abnormal brain performance.
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From page 42...
... TES has been used for this purpose, although it can only be done intraoperatively. However, Chen described recent studies using TMS presurgically to map the motor cortex; those studies indicate that this approach reliably predicts TES responses (Galloway et al., 2013; Krieg et al., 2013; Picht et al., 2013)
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From page 43...
... . Alexander Rotenberg noted that because stimulating a part of the brain can evoke a measurable response, neurostimulation coupled with electrophysiologic recording techniques may provide biomarkers for disease states that could be modulated neurostimulation, or even serve as stand-alone biomarkers.
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Key Terms

  • brain performance
  • motor neuron
  • upper motor
  • neuromuscular disorders
  • motor cortex

  • cord lesions
  • neuron involvement
  • multiple sclerosis
  • abnormal brain
  • cortical inhibition

  • presurgical mapping
  • avoid damage
  • performing saccade
  • studies using
  • tms presurgically

  • reach tasks
  • brain conditions
  • predict response
  • robiologic processes
  • mimic disorders

  • measurable response
  • subthalamic nucleus
  • therapeutic devices
  • scribed recent
  • document lesions

  • electrophysiologic recording
  • cortex excitability
  • provide biomarkers
  • recording techniques
  • identify eloquent


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