Iron Deficiency Anemia Recommended Guidelines for the Prevention, Detection, and Management Among U.S. Children and Women of Childbearing Age (1993) / Chapter Skim
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RECOMMENDATIONS FOR RESEARCH
RECOMMENDATIONS FOR RESEARCH
Pages 26-31
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From page 26... ...
Thus, the hemoglobin concentration was increased, and therefore, it is unclear whether hemoglobin levels could also be raised among women with inadequate plasma volume expansion and whether it would possibly cause problems associated with a high hemoglobin concentration. Also, among women who received supplemental iron in controlled trials of iron supplementation during pregnancy, the weighted value of the mean plus two standard deviations for the hemoglobin concentration closest to term (between 36 and 40 weeks)
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From page 27... ...
27 no i_ o 4_ U)
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From page 28... ...
The first assumption is that the adverse outcomes associated with high hemoglobin concentrations have little or nothing to do with red blood cell mass but, rather, are a function of contracted or inadequately expanded plasma volume. This assumption needs testing in an observational study that asks the following: Are high hemoglobin concentrations with adequately expanded plasma volume associated with an adverse outcome, or are only high hemoglobin concentrations associated with inadequately expanded plasma volume?
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From page 29... ...
Research Base for Public Policy Improved Data on Iron in the Food Supply To more accurately determine the impact of iron fortification on dietary intake, the committee recommends improvement in the database on the types of iron used to fortify foods, the quantity of iron added to those foods, and the iron usage patterns by population subgroups (race, gender, and income and in relation to patterns of serum ferritin concentrations)
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From page 30... ...
For adolescent males, more information on the effect of iron intake and athletic performance and endurance is needed. New Determinants of Iron Deficiency Anemia in the First Trimester of Pregnancy A key issue confronting the committee was the ability of clinicians and public health practitioners to identify early in pregnancy women who are at risk for developing iron deficiency anemia in the first trimester of pregnancy.
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From page 31... ...
Therefore, the committee recommends that more information be collected about the costs and benefits of alternative approaches for preventing and detecting iron deficiency anemia There is little information in the literature about the efficacy or effectiveness of alternative intervention strategies, and the committee therefore did not find it surprising that little information is available on the cost-benefit attributes of alternative public health approaches. Some straightforward studies on the cost implications of policy changes in the types of laboratory tests used to evaluate iron nutrition and the presence of iron deficiency anemia should be undertaken.
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