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Appendix F: Primary and Subsidiary Hypotheses of the Women's Health Initiative Clinical Trial
Pages 113-114

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From page 113...
... : DM—in the form of a low-fat dietary pattern (reduced intake of total fat and saturated fat, increased intake of complex carbohydrate and fiber-containing foods) will reduce the incidence of breast cancer and colorectal cancer, separately.
From page 114...
... However, subgroup analyses wall be performed to examine: The effect of DM plus HRT on breast cancer incidence in women at high and low risk of breast cancer. The effect of DM plus HRT on the incidence of coronary and other cardiovascular disease and breast cancer, compared with each therapy alone.


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