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Appendix B: Food Allergy Prevalence Literature Search Strategy
Pages 397-438

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From page 397...
... Articles were excluded if they were written in a language other than English, had nonhuman subjects, or were case studies/series, notes, conference abstracts, nonsystematic reviews, or opinion pieces. The searches yielded 767 unduplicated articles.
From page 398...
... a Search was designed to capture studies measuring the prevalence of food allergy and anaphylaxis to peanut, nut, milk, wheat, egg, soy, fish, shellfish, or sesame, and was not limited by country. b Supplemental search was designed to capture studies measuring the prevalence of food allergy and anaphylaxis to additional allergens not included in initial search (see text for complete list)
From page 399...
... EMBASE Search  1 Food allergy/  2 Food allergen/  3 Peanut allergy/  4 Nut allergy/  5 Milk allergy/  6 Wheat allergy/  7 Egg allergy/  8 Soy allergy.mp  9 Soybean allergy.mp 10 Fish allergy.mp 11 Shellfish allergy.mp 12 Sesame allergy.mp 13 1 or 2 or 3 or 4 or 5 or 6 or 7 or 8 or 9 or 10 or 11 or 12 14 Prevalence/ 15 Anaphylaxis/ 16 Food allergy prevalence.mp 17 Life threatening food allergy.mp 18 14 or 15 or 16 or 17 19 13 and 18 NOTES: Search terms were mapped to Subject Headings when available; otherwise searched as Keyword (.mp)
From page 400...
... 7 Food Hypersensitivity/ 8 limit 7 to (English language and humans and yr="2012 -Current") 9 Skin Tests/ 10 Immunoglobulin E/ 11 2 or 4 12 6 or 8 or 9 or 10 13 11 and 12 14 Milk/ 15 13 and 14 16 Egg Hypersensitivity/ 17 13 and 16 18 Milk Hypersensitivity/ 19 13 and 18 20 Fishes/ 21 Tuna/ 22 Salmon/ 23 Gadiformes/ 24 20 or 21 or 22 or 23 25 13 and 24 26 Nut Hypersensitivity/ 27 Prunus/ 28 Macadamia/ 29 Bertholletia/ 30 Carya/
From page 401...
... APPENDIX B 401 TABLE B-2 Continued Search Numbers Search Terms 31 Anacardium/ 32 Nuts/ 33 Pistacia/ 34 Corylus/ 35 Juglans/ 36 pine nut.mp. 37 chestnut.mp.
From page 402...
... 7 food allergy/ 8 limit 7 to (human and English language and yr="2012 -Current") 9 skin test/ 10 immunoglobulin E/ 11 2 or 4 12 6 or 8 or 9 or 10 13 11 and 12 14 milk allergy/ 15 egg allergy/ 16 fish/ 17 salmon/ 18 tuna/ 19 Atlantic cod/ 20 Crustacea/ 21 shellfish/ 22 shrimp/ 23 lobster/ 24 crab/ 25 mollusc/
From page 403...
... . Searches limited to human studies, English language, and published 2012 to Current.
From page 404...
... McGowan et US Cross-sectional N/A NHANES III al., 2016 (1988-1994)
From page 405...
... NHANES 2005-2006: 21.6 (19.5-23.7) Shrimp sensitization NHANES III: 11.2 (10.0-12.5)
From page 406...
... 406 FINDING A PATH TO SAFETY IN FOOD ALLERGY TABLE B-3  Continued Number Invited or Eligible Participation Rate Reference Country Study Design Participants N (%) Schoemaker et Europe Cohort 12,049 9,336 (77%)
From page 407...
... Adults and children Peanut, tree nuts, Self-report, Self-reported food fish, shellfish, convincing history, allergy to any food sesame, milk, egg, physician diagnosis wheat, and/or soy Full participants: 6.4 (6.0-6.8) (unweighted)
From page 408...
... 408 FINDING A PATH TO SAFETY IN FOOD ALLERGY TABLE B-3  Continued Number Invited or Eligible Participation Rate Reference Country Study Design Participants N (%) Bunyavanich US Cohort study 1,277 616 (48.2)
From page 409...
... 20-54 years Various Self-report, Self-report: 21.0 physician Physician diagnosis: diagnosis, sIgE 4.4 (≥0.35 kUA/L) IgE to any foods: 15.81 0-3 years Various Self-report Ever had a food 4-6 years allergy 0-3 years: 8.6 (6.4-11.5)
From page 410...
... 410 FINDING A PATH TO SAFETY IN FOOD ALLERGY TABLE B-3  Continued Number Invited or Eligible Participation Rate Reference Country Study Design Participants N (%) Kaya et al., Turkey Cross-sectional 11,233 10,096 (89.9)
From page 411...
... Parent-reported point prevalence: 3.6 Confirmation by: (3.2-3.8) clinical history, sIgE, SPT, OFC, Confirmed food DBPCOFC allergy: 0.15 Confirmed peanut: 0.05 Confirmed tree nut: 0.05 0-17 years All allergens Parent report Urban centers: 9.8 (peanut, shellfish, of physician (8.6-11.0)
From page 412...
... Ben-Shoshan Canada Cross-sectional 8,039 (64) et al., 2009 Branum and US Cross-sectional Not indicated Not indicated Lukacs, 2009 NOTE: CI = confidence interval; DBPCOFC = double-blind, placebo-controlled oral food challenge; IgE = immunoglobulin E; N/A = not applicable; OFC = oral food challenge; SE = standard error; sIgE = food-specific serum IgE; SPT = skin prick test; UK = United Kingdom; US = United States.
From page 413...
... <18 years Peanut, tree nuts, Self-report Peanut: 1.4 (1.0-1.9) sesame Tree nuts: 1.1 Sesame: 0.1 (0-0.2)
From page 414...
... Types of participants: Selected patient groups or those   •  performed in hospital or allergy clinic settings. Literature search dates January 1996 to December 2014 or year range Number of food allergy 36 studies included Synthesis methods Summary tables, narrative text, meta-analysis
From page 415...
... Pollen-associated food allergy: Prevalence estimates that included pollen-associated food allergy reactions to tree nut were significantly higher (8-11.4%) and were predominantly from Europe.
From page 416...
... Y/N (COI of the systematic review authors was provided but not provided for included studies) Author, year Umasunthar et al., 2015 Aims/Key questions To quantify the risk of anaphylaxis for food-allergic people Study eligibility criteria Inclusion criteria: Study design: Prospective or retrospective registries,   •  databases or cohort studies.
From page 417...
... The rate of medically coded anaphylaxis also varied widely between studies. These data may underestimate food anaphylaxis occurrence.
From page 418...
... Exclusion criteria:   •  ypes of studies: narrative reviews; studies of people older T than age 19 years; studies lacking sufficient congruence and/or yield between what was described in the objectives and what was reported. Literature search dates or 1909 to March 2013 year range Number of food allergy 40 studies included Synthesis methods Summary tables, meta-analysis
From page 419...
... AMSTAR rating An a priori design? Y Duplicate study selection and data extraction?
From page 420...
... T Literature search dates or Up to February 2012 year range Number of food allergy 27 survey administrations (20 survey administrations were used studies included in the meta-regression) Synthesis methods Summary tables, narrative text, meta-analysis with meta-regression
From page 421...
... AMSTAR rating An a priori design? Y Duplicate study selection and data extraction?
From page 422...
... Literature search dates or January 2000 to September 30, 2012 year range Number of food allergy 65 (based on 50 primary studies) studies included Synthesis methods Summary tables, narrative text, meta-analysis Key findings Self-reported food allergy: The overall pooled estimates for all age groups of self-reported lifetime prevalence of allergy to cow milk, egg, wheat, soy, peanut, tree nuts, fish, and shellfish were 6.0% (95% CI: 5.7%-6.4%)
From page 423...
... Exclusion criteria:   •  ypes of studies: Systematic reviews, meta-analyses, T abstracts, gray literature, and non-US studies. Literature search dates or Not provided year range Number of food allergy 20 studies included Synthesis methods Summary tables, narrative text continued
From page 424...
... Y/N (COI of the systematic review authors was provided but not provided for included studies)
From page 425...
... Exclusion criteria:   •  ypes of studies: Articles from the Middle East and Turkey; T non-English studies. Literature search dates or January 2005 to December 2012 year range Number of food allergy 53 studies included Synthesis methods Summary table, narrative text Key findings The overall prevalence of food allergy in Asia is somewhat comparable to the West.
From page 426...
... Literature search dates or January 1, 2000, to September 30, 2012 year range Number of food allergy 49 (3 included in meta-analysis) studies included Only 10 were food allergy studies and none of these was in the meta-analysis Synthesis methods Summary tables, narrative text, meta-analysis Key findings Meta-analysis yielded a pooled estimated prevalence of anaphylaxis, due to any cause, of 0.3% (95% CI 0.1%-0.5%)
From page 427...
... Y Duplicate study selection and data extraction? Y Comprehensive literature search?
From page 428...
... Y Duplicate study selection and data extraction? Y Comprehensive literature search?
From page 429...
... or systematic reviews. Literature search dates or January 1988 to September 2009 year range Number of food allergy 6 studies on prevalence of food allergy studies included Synthesis methods Narrative text continued
From page 430...
... Y Duplicate study selection and data extraction? Y Comprehensive literature search?
From page 431...
... Literature search dates or January 1990 to December 2006 year range Number of food allergy 36 (33 publications) studies included Synthesis methods Summary tables, meta-analysis continued
From page 432...
... among the seven studies regarding perception of allergy caused by fruits (summary prevalence estimate, 1.22%; 95% CI: 0.82%-1.63%) , vegetables (six studies: 0.98%; 95% CI: 0.52%-1.45%)
From page 433...
... Y/N (COI of the systematic review authors was provided but not provided for included studies) continued
From page 434...
... Excluded articles when the original community sample was enriched with a sample including patients, or the sample size was not provided. Literature search dates or January 1990 to December 2005 year range Number of food allergy 51 studies included Synthesis methods Narrative text, summary tables, meta-analysis Key findings The studies showed marked heterogeneity regardless of type of assessment or food item considered, and in most analyses this persisted after age stratification.
From page 435...
... NOTE: CDC = Centers for Disease Control and Prevention; CI = confidence interval; DBPCOFC = double-blind, placebo-controlled oral food challenge; IgE = immunoglobulin E; NHANES = National Health and Nutrition Examination Survey; NHIS = National Health Interview Survey; sIgE = food-specific serum IgE; SPT = skin prick test; UK = United Kingdom; US = United States.
From page 436...
... 2013. Racial and ethnic disparity in food allergy in the United States: A systematic review.
From page 437...
... 2014. Prevalence of allergic sensitization in the United States: Results from the National Health and Nutrition Examination Survey (NHANES)
From page 438...
... 2016. Incidence and natural history of hen's egg allergy in the first 2 years of life -- The EuroPrevall birth cohort study.


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