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Pages 1-4

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From page 1...
... ditional approach are that chemicals on which data are insufficient are typically treated as not hazardous, that ORGANOHALOGEN FLAME untested chemicals are often substituted for hazardous RETARDANTS AND THE PETITION chemicals, and that cumulative exposure and risk are often ignored. One method of assessing multiple chemicals In the 1970s, flame retardants began to be added to is a class approach in which chemicals that have simi- synthetic materials to meet strict flammability standards.
From page 2...
... polyhalogenated bisphenol aliphatics -- to illustrate vari- • Option 3-3: Generate toxicity data on data-poor ous aspects of its proposed scoping plan. In conducting subclass members to the extent that satisfactory its case studies, the committee identified four scenarios confidence is gained; testing could involve NAM that would likely arise in a class-based hazard assessment studies, targeted animal testing, or a combination of OFRs.
From page 3...
... Expand Yes Subclass, or Reclassify End Point A End Point B End Point C Hazard Assessment Search Literature to Identify All Relevant Data Extract Data Discordant Evaluate and Integrate Data Data "Potentially Hazardous" "Not Hazardous" Perform Analyses, Generate New Data, Reclassify, or Risk Assessment Make Policy for Subclass Decision FIGURE S-1 Scoping plan to conduct a hazard assessment for the Consumer Product Safety Commission (CPSC) by using a class approach.
From page 4...
... toxicology to assessing the hazards posed by OFRs. A class approach studies will require resources that are orders of magnitude will likely result in increases in efficiency and decreases greater than would be needed if NAM data or a combina- in cost compared with the traditional approach of evalution of NAM data and targeted animal studies were used.


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