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Review of EPA's Updated Problem Formulation and Protocol for the Inorganic Arsenic IRIS Assessment (2019) / Chapter Skim
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... EPA has implemented systematic review approaches to evaluate the scientific literature and has appropriately prioritized the health outcomes for dose-response assessment. EPA has begun to implement several analytical approaches to utilize human data in the low-dose range, and has introduced more advanced statistical methods in its dose-response evaluations that take into consideration human data from multiple studies.
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Key Terms

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  • inorganic arsenic
  • human data
  • review methods
  • ias toxicity
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  • arsenic iris
  • lower doses
  • epidemiological studies
  • integrated risk
  • analysis techniques

  • recently released
  • life exposures
  • review approaches
  • hoc committee
  • implemented systematic

  • multiple studies
  • health outcome
  • various elements
  • contextual information
  • materials address

  • lower range
  • vanced statistical
  • analytical approaches
  • prioritizing health
  • committee commends


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