Skip to main content

Forum on Drug Discovery, Development, and Translation 2018 Annual Report (2019) / Chapter Skim
Currently Skimming:

Action Collaboratives
Pages 14-17

The Chapter Skim interface presents what we've algorithmically identified as the most significant single chunk of text within every page in the chapter.
Select key terms on the right to highlight them within pages of the chapter.


From page 14...
... However, there is a need to identify key gaps in the knowledge base and other barriers that impede progress and to develop an approach for addressing them. This action collaborative launched in 2017 to foster the development of a strategic research framework to advance the science of 1 Each action collaborative is an ad hoc activity associated with the Forum at the National Academies.
Read the entire page →
From page 15...
... Clinical Trial Site Standards Harmonization Mobilized in 2012, this action collaborative set out to explore opportunities to improve clinical trial site functioning with the goal of increasing productivity in medical product development. To date, the collaborative has drawn together a group of diverse stakeholders for four in-person meetings (December 2012, August 2013, March 2014, and September 2018)
Read the entire page →
From page 16...
... The goal of this action collaborative is to examine the contributing factors to late-stage failures and develop a set of key considerations for stakeholders to improve the probability of success in late-stage product development. In 2018, collaborative participants conducted structured, qualitative interviews with subject-matter experts; analyzed and synthesized responses from these interviews; considered information compiled from a literature survey; and held a meeting on October 3, 2018, to discuss and inform the key considerations.
Read the entire page →
From page 17...
... These opportunities and challenges were laid out in the IOM report Sharing Clinical Trial Data: Maximizing Benefits, Minimizing Risk, which calls on stakeholders to foster a culture of sharing and offers a blueprint for action within and across sectors. Four National Academies forums and Action collaboratives engage roundtables, including the Forum, provided momentum and a framework for initiating experts with similar interests the consensus study that produced the report and continue to work together to support coordination and collaboration among stakeholders engaged in data-sharing and responsibilities to analyze initiatives through convening and other activities.
Read the entire page →

Key Terms

  • action collaborative
  • action collaboratives
  • medical product
  • clinical trials
  • collaborative participants

  • patient input
  • sharing clinical
  • trial site
  • trial data
  • trial sites

  • site standards
  • study reports
  • nonprofit funders
  • collaboratives engage
  • consensus study

  • identified goals
  • baseline clinical
  • improve clinical
  • clinical researchers
  • disease advocacy

  • global data
  • participants published
  • collaborative set
  • participants conducted
  • sharing goals

  • product developers
  • site functioning
  • collaborative launched
  • information sharing
  • incorporate patient


    • This material may be derived from roughly machine-read images, and so is provided only to facilitate research.
    More information on Chapter Skim is available.