Forum on Neuroscience and Nervous System Disorders 2014 Annual Report (2015) / Chapter Skim
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Forum on Neuroscience and Nervous System Disorders: 2014 Annual Report
Forum on Neuroscience and Nervous System Disorders: 2014 Annual Report
Pages 1-16
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BOARD ON HEALTH SCIENCES POLICY Forum on Neuroscience and Nervous System Disorders 2014 Annual Report
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The Forum meets two to three times per year and provides its members with a structured, neutral venue for exchanging information, ideas, and differing points of view. At its meetings, the Forum examines significant -- and sometimes contentious -- issues concerning science, priority setting, and policy related to neuroscience research, nervous system disorders, and the development, regulation, and clinical use of interventions for the nervous system.
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Looking ahead to 2015, the Forum plans an array of activities on topics such as: • C ountry-specific opportunities in Ghana and Kenya to improve the health system infrastructure in order to develop sustainable access to mental health care; • C onsideration of approaches to increase private-sector investments in the discovery and development of novel therapeutics to address unmet needs for nervous system disorders; • D iscovery, development, and translation of treatments for cognitive dysfunction in depression; and • O pportunities, challenges, and ethical questions surrounding therapeutic and non-therapeutic uses of non-invasive neuromodulation of the central nervous system. We look forward to another productive year for the Forum.
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The Forum hosted an activity to address challenges and examine potential strategies to facilitate better management and greater sharing of large basic research datasets. Training the Next Generation of Neuroscientists From its beginning, neuroscience has been fundamentally interdisciplinary.
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To address these issues, the Forum hosted a workshop that explored future workforce needs and considered the design of training pro grams. Current and new components of training programs were discussed to identify methods for enhancing data handling and analysis capabilities, increasing scientific rigor, and improving research practices.
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To address the need for reliable, sustainable access to safer and more effective medicines, the Forum hosted a meeting that assembled key stakeholders to discuss oppor tunities for providing access to essential medicines for MNS disorders with a focus on depression, psychotic disorders, and epilepsy. Specifically, par ticipants examined successful models of treatment delivery and examples of effective supply chains for infectious diseases and several noncommuni cable diseases in SSA and in low- and middle-income countries outside SSA.
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Given the high prevalence of gaming in today's society, the Forum hosted a Social Issues Roundtable at the Society for Neuroscience 2014 annual meeting, bringing together key stakeholders who explored the neuroscience of electronic gaming, with emphasis on rel evant scientific, ethical, and societal issues. Aug 4–5 Feb 25 Jun 17 Sub-Saharan Africa 8th meeting 9th meeting Workshop 2009 2009 Jun 16 Oct 18 Suicidality Workshop SFN: Social Issues Roundtable
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Recognizing the importance of sustainable mental health care, these work shops will bring together key stakeholders to examine country-specific opportuni ties in Ghana and Kenya to improve and develop sustainable access to mental health to ensure that the right patients get the right care and treatment at the right time in the right setting. Financial Incentives to Address Unmet Medical Needs for Nervous System Disorders The global burden of nervous system disorders is projected to increase signifi cantly over time and is estimated to cost society more than $6 trillion per year by 2030 (according to the report "The Global Economic Burden of Noncommunicable Diseases" by World Economic Forum and Harvard School of Public Health)
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Enabling Development, Discovery, and Translation for Cognitive Dysfunction in Depression Depression is a highly prevalent and disabling disorder for which existing treat ments (including both medications and psychotherapies) are only partly effective for some patients and ineffective for many.
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The workshop will bring together key stakeholders to explore ways to improve the discovery, development, and regulatory path for new treatments addressing this aspect of depression. Non-Invasive Neuromodulation of the Central Nervous System Based on advances in biotechnology and neuroscience, neuromodulation devices are poised to gain clinical importance in the coming years and to be of increasing interest to patients, health care providers and payers, and industry.
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The workshop will explore potential data sharing and data management strategies as well as the infrastructure necessary to identify surrogate outcomes for Alzheimer's disease research. Current computational approaches to health care data will be discussed to identify methods for analyzing digital health data that already exist for patients, for increasing data sharing, and for improving clinical research practices.
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Exploring Financial Incentives to Improve Neuroscience Research and Development Innovation for Drug Discovery and Development The Forum established a working group that will explore potential financial incentives that could spur additional investment from the private sector in translational neuroscience research and development that would focus on novel treatment mechanisms and unmet medical needs. To begin this effort, the Forum convened a working group to develop a set of two or three incentives that could lead to significant reinvestment by large pharmaceutical companies in central nervous system disorders.
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Special attention is being paid Workshop Summary to finding solutions to increase human and financial resources to support current and future efforts. Jan 13-14 Mar 2-3 Apr 28-29 Jul 18-23 Nov 15 Providing Sustainable Non-Invasive Providing Sustainable Assessing the Impact of Dry AMD Access to Mental Health Neuromodulation Access to Mental Health Applications of Digital Health Workshop Care: Kenya Workshop Workshop Care: Ghana Workshop Records on Alzheimer's Disease 2015 Nov 16 Jan 20-21 Feb 24 Jun 4-5 Nov 10 The Neuroscience Financial Incentives Cognitive Dysfunction in 24th meeting 25th meeting of Gaming Workshop Workshop Depression Workshop
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William Dunn Husseini Manji Broad Institute of the Massachusetts Food and Drug Administration Johnson & Johnson Pharmaceuticals Institute of Technology and Harvard Emmeline Edwards David Michelson University National Center for Complementary Merck Research Laboratories Story Landis (Vice-Chair) and Integrative Health Richard Mohs Former Director, National Institute of Martha Farah Eli Lilly and Company Neurological Disorders and Stroke University of Pennsylvania James Olds Susan Amara Daniel Geschwind National Science Foundation Society for Neuroscience University of California, Los Angeles Atul Pande Mark Bear Hank Greely Tal Medical Massachusetts Institute of Stanford University Technology Steven Paul Magali Haas Weill Cornell Medical College Stephen Brannan Orion Bionetworks Takeda Pharmaceuticals Todd Sherer International, Inc.
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Alzheimer's Association Brain Canada Nonprofit Department of Veterans Affairs Food and Drug Administration 9% Foundation for the National Institutes of Health Gatsby Charitable Foundation GlaxoSmithKline Johnson & Johnson Pharmaceuticals Federal Lilly Research Laboratories 50% Lundbeck USA 41% Industry Merck Research Laboratories The Michael J Fox Foundation for Parkinson's Research National Eye Institute National Center for Complementary and Integrative Health National Institute of Mental Health National Institute of Neurological Disorders and Stroke National Institute on Aging National Institute on Alcohol Abuse and Alcoholism National Institute on Drug Abuse National Institutes of Health Blueprint for Neuroscience Research National Multiple Sclerosis Society National Science Foundation One Mind for Research Orion Bionetworks Pfizer, Global Research and Development Pharmaceutical Product Development, Inc.
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The Institute of Medicine serves as adviser to the nation to improve health. Established in 1970 under the charter of the National Academy of Sciences, the Institute of Medicine provides independent, objective, evidence-based advice to policy makers, health professionals, the private sector, and the public.
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