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Forum on Neuroscience and Nervous System Disorders: 2015 Annual Report
Pages 1-20

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From page 1...
... HEALTH AND MEDICINE DIVISION BOARD ON HEALTH SCIENCES POLICY Forum on Neuroscience and Nervous System Disorders 2015 Annual Report
From page 2...
... Initiative; the state of financial incentives to encourage research and development of treatments for unmet needs in central nervous system (CNS) disorders; a possible new focus on cognitive dysfunction in depression; the opportunities and challenges related to non-invasive neuromodulation devices; the use of digital health records for Alzheimer's disease research; and the continuation of efforts to improve mental and neurological health care in the developing world, with a focus this past year on Ghana and Kenya.
From page 3...
... Steven Hyman Story Landis Chair Vice-Chair
From page 4...
... Currently available treatments have only modest benefits in treating cognitive dysfunction in depression, and some treatments, especially February 26 Biomarkers Workshop FORUM ACTIVITIES TIMELINE 2006 2007 October 4-5 February 27 1st Meeting 2nd Meeting
From page 5...
... The Forum convened key stakeholders to explore how best to enable the discovery, development, and translation of treatments for cognitive dysfunction in depression, including a focus on the regulatory path forward. Non-Invasive Neuromodulation of the Central Nervous System Because of advances in biotechnology and neuroscience, non-invasive neuro modulation devices are of increasing interest to clinicians, patients, health systems, and payers and could acquire significant clinical importance in the coming years.
From page 6...
... The Forum hosted a session at the 2015 Alzheimer's Association International Conference to explore how digital health records might be used to help improve clinical trial design and methodology for Alzheimer's disease research. The session brought together an international group of experts in translational, epidemiological, and health services research along with an ethicist and representative of a big data analytics company.
From page 7...
... November 9 March 8-9 Animal Law Sex Differences June 23 July 12 Workshop Workshop 11th Meeting ICAD 2010 Session 2010 November 3 June 22 December 10 10th Meeting Glutamate Workshop 12th Meeting
From page 8...
... Better methods, from clinical study design through execution and evaluation, could help enhance the integrity, feasibility, acceptability, efficiency, and economic viability of clinical neuropsychiatric development. The Forum will convene a public workshop to bring together key stakeholders to discuss ways to advance thera peutic development for nervous system disorders by using innovative clinical trial designs; improving patient selection, engagement, and retention; and enhancing clinical monitoring to help decrease the failure rate of drugs and devices in development.
From page 9...
... For example, the workshop might explore the possibility of new public–private partnerships to establish biomarkers, learning from the successes and difficulties of the Alzheimer's Disease Neuroimaging Initiative or new diagnostic scales October 4-5 March 28-29 July 11 Sharing Clinical Animal Models Workshop 17th Meeting Research Data Workshop March 28 May 10-11 September 4-5 November 18 16th Meeting Neurodegeneration SSA Human Resources 18th Meeting Workshop Workshop
From page 10...
... Responsible Innovation and the Brain -- Societal Dimensions of Neurotechnology Advances Emerging neurotechnologies have the potential to enhance human lives, offering better health outcomes and higher quality of life through the prevention and treatment of mental illness and neurological disease. But the scientific advances that have given rise to these new technologies raise a host of ethical, legal, and social issues.
From page 11...
... Looking Forward: Forum Activities in 2016 January 13-14 Providing Sustainable Access June 17 November 15 to Mental Health Care: Kenya 22nd Meeting Dry AMD Workshop Workshop 2015 October 28 November 16 January 20-21 23rd Meeting The Neuroscience of Financial Incentives Gaming Session at SfN Workshop
From page 12...
... July 20 April 28-29 Assessing the Impact of February 24 Providing Sustainable Access Applications of Digital Health Cognitive Dysfunction in to Mental Health Care: Ghana Records on Alzheimer's Disease Depression Workshop Workshop Research Session at AAIC March 2-3 June 4-5 November 10 Non-Invasive 24th Meeting 25th Meeting Neuromodulation Workshop
From page 13...
... June 14-15 27th meeting and February 23 Multimodal Therapies September 15-16 26th Meeting Workshop OECD Workshop 2016 March 3-4 September 12-13 Neuroscience Trials of Development in the Absence the Future Workshop of Animal Models Workshop
From page 14...
... 2015 Publications Developing a 21st Century Financial Incentives to Encourage Neuroscience Workforce: Development of Therapies That Workshop Summary Address Unmet Medical Needs for Nervous System Disorders: Workshop Summary
From page 15...
... Enabling Discovery, Non-Invasive Neuromodulation Development, and Translation of the Central Nervous System: of Treatments for Cognitive Opportunities and Challenges: Dysfunction in Depression: Workshop Summary Workshop Summary
From page 16...
... 2015 Publications Providing Sustainable Mental Assessing the Impact of and Neurological Health Care Applications of Digital Health in Ghana and Kenya: Workshop Records on Alzheimer's Disease Summary Research: Workshop Summary
From page 17...
... Advancing Therapeutic The Neuroscience of Gaming: Development for Dry Age– Workshop in Brief Related Macular Degeneration (AMD) : Workshop in Brief
From page 18...
... Thomas Caskey The Michael J Fox Foundation for John Isaac Parkinson's Research Baylor College of Medicine Wellcome Trust Karen Chandross David Shurtleff Inez Jabalpurwala National Center for Complementary Sanofi Brain Canada Foundation and Integrative Health Timothy Coetzee Frances Jensen National Multiple Sclerosis Society Paul Sieving University of Pennsylvania Health National Eye Institute Fay Lomax Cook System National Science Foundation Nora Volkow George Koob National Institute on Drug Abuse Bruce Cuthbert National Institute on Alcohol Abuse National Institute of Mental Health and Alcoholism Stevin Zorn Lundbeck USA
From page 19...
... Alzheimer's Association Brain Canada Foundation Cohen Veterans Bioscience Department of Veterans Affairs Eli Lilly and Company Food and Drug Administration Foundation for the National Institutes of Health Gatsby Charitable Foundation Nonprofit Genzyme, a Sanofi Company Janssen Research & Development, LLC 12% Lundbeck USA Merck Research Laboratories The Michael J Fox Foundation for Parkinson's Research National Center for Complementary and Integrative Health National Eye Institute National Institute of Mental Health 52% Federal National Institute of Neurological Disorders and Stroke Industry 36% National Institutes of Health Blueprint for Neuroscience Research National Institute on Aging National Institute on Alcohol Abuse and Alcoholism National Institute on Drug Abuse National Multiple Sclerosis Society National Science Foundation One Mind Pfizer Inc.
From page 20...
... At its The National Academy of Engineering was established in 1964 under meetings, the Forum examines significant -- and sometimes contentious -- the charter of the National Academy of Sciences to bring the practices issues concerning scientific needs and opportunities, priority setting, and of engineering to advising the nation. Members are elected by their policies related to neuroscience research, its societal implications, and peers for extraordinary contributions to engineering.


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